Antrag/LogSeq/assets/1-s2.0-S1120179720302362-main_Metrology_for_flash_1704659443526_0.edn

230 lines
14 KiB
Clojure
Raw Normal View History

2024-01-11 11:03:18 +00:00
{:highlights [{:id #uuid "659b0a42-721f-4625-be01-6549df80fa12",
:page 2,
:position {:bounding {:x1 62.640625,
:y1 752.421875,
:x2 481.1163330078125,
:y2 802.296875,
:width 992.1266683333332,
:height 1322.8349816666666},
:rects ({:x1 82.578125,
:y1 752.421875,
:x2 481.1163330078125,
:y2 767.421875,
:width 992.1266683333332,
:height 1322.8349816666666}
{:x1 62.640625,
:y1 769.90625,
:x2 481.08282470703125,
:y2 784.90625,
:width 992.1266683333332,
:height 1322.8349816666666}
{:x1 62.640625,
:y1 787.296875,
:x2 481.08416748046875,
:y2 802.296875,
:width 992.1266683333332,
:height 1322.8349816666666}),
:page 2},
:content {:text "FLASH radiotherapy (FLASH-RT) is a promising cancer treatment under development, that involves an almost instantaneous delivery of a high radiation dose in only a few radiation pulses of ultra-high dose rate."},
:properties {:color "yellow"}}
{:id #uuid "659b0b80-3beb-4b61-9f5e-12965650cedb",
:page 2,
:position {:bounding {:x1 70.15625,
:y1 1233.34375,
:x2 539.09375,
:y2 1386.078125,
:width 1111.181868533333,
:height 1481.5751794666667},
:rects ({:x1 189.21115112304688,
:y1 1233.34375,
:x2 538.7996215820312,
:y2 1249.34375,
:width 1111.181868533333,
:height 1481.5751794666667}
{:x1 70.15625,
:y1 1252.921875,
:x2 539.09375,
:y2 1268.921875,
:width 1111.181868533333,
:height 1481.5751794666667}
{:x1 70.15625,
:y1 1272.390625,
:x2 538.887451171875,
:y2 1288.390625,
:width 1111.181868533333,
:height 1481.5751794666667}
{:x1 70.15625,
:y1 1291.96875,
:x2 296.9447021484375,
:y2 1307.96875,
:width 1111.181868533333,
:height 1481.5751794666667}
{:x1 92.484375,
:y1 1311.53125,
:x2 538.8486328125,
:y2 1327.53125,
:width 1111.181868533333,
:height 1481.5751794666667}
{:x1 70.15625,
:y1 1331.03125,
:x2 538.7847290039062,
:y2 1347.03125,
:width 1111.181868533333,
:height 1481.5751794666667}
{:x1 70.15625,
:y1 1350.59375,
:x2 538.8189697265625,
:y2 1366.59375,
:width 1111.181868533333,
:height 1481.5751794666667}
{:x1 70.15625,
:y1 1370.078125,
:x2 538.8873901367188,
:y2 1386.078125,
:width 1111.181868533333,
:height 1481.5751794666667}),
:page 2},
:content {:text "The limited energy of medical electron beams, only suitable for treatment of superficial or shallow tumours, boost treatments and operative scars [26], becomes a significant obstacle for treatment of deep-seated tumours. The application of very high energy electron (VHEE) [27] beams with energies exceeding 100 MeV could address the limitation of penetration depth and allow a therapeutic dose to be delivered to a deepseated tumour using FLASH regimes but requires huge accelerators for"},
:properties {:color "yellow"}}
{:id #uuid "659b0bce-2a9f-4f58-9fc3-274297d5c510",
:page 2,
:position {:bounding {:x1 572.296875,
:y1 119.953125,
:x2 1040.98779296875,
:y2 233.515625,
:width 1111.181868533333,
:height 1481.5751794666667},
:rects ({:x1 594.625,
:y1 119.953125,
:x2 1040.986328125,
:y2 135.953125,
:width 1111.181868533333,
:height 1481.5751794666667}
{:x1 572.296875,
:y1 139.421875,
:x2 1040.8941650390625,
:y2 155.421875,
:width 1111.181868533333,
:height 1481.5751794666667}
{:x1 572.296875,
:y1 159,
:x2 1040.903076171875,
:y2 175,
:width 1111.181868533333,
:height 1481.5751794666667}
{:x1 572.296875,
:y1 178.46875,
:x2 1040.98779296875,
:y2 194.46875,
:width 1111.181868533333,
:height 1481.5751794666667}
{:x1 572.296875,
:y1 198.046875,
:x2 1040.9521484375,
:y2 214.046875,
:width 1111.181868533333,
:height 1481.5751794666667}
{:x1 572.296875,
:y1 217.515625,
:x2 957.1112670898438,
:y2 233.515625,
:width 1111.181868533333,
:height 1481.5751794666667}),
:page 2},
:content {:text "The actual accelerator structure of a laser driven electron accelerator is only a few cm in size and can reach energies up to GeV [28]. Laserdriven particle accelerators, which are being considered as the next generation of compact and cost-effective accelerators for radiotherapy with VHEE [29] as well as protons [30], can deliver ultra-short radiation pulses of extremely high dose rate (up to 109 1012 Gy/s)"},
:properties {:color "yellow"}}
{:id #uuid "659b0cb3-7710-4992-85c4-a42d38baa74f",
:page 6,
:position {:bounding {:x1 70.15625,
:y1 256.578125,
:x2 538.87548828125,
:y2 331.203125,
:width 1111.181868533333,
:height 1481.5751794666667},
:rects ({:x1 323.60400390625,
:y1 256.578125,
:x2 538.87548828125,
:y2 272.578125,
:width 1111.181868533333,
:height 1481.5751794666667}
{:x1 70.15625,
:y1 276.15625,
:x2 538.8709716796875,
:y2 292.15625,
:width 1111.181868533333,
:height 1481.5751794666667}
{:x1 70.15625,
:y1 295.625,
:x2 538.8487548828125,
:y2 311.625,
:width 1111.181868533333,
:height 1481.5751794666667}
{:x1 70.15625,
:y1 315.203125,
:x2 481.91693115234375,
:y2 331.203125,
:width 1111.181868533333,
:height 1481.5751794666667}),
:page 6},
:content {:text "However, extended studies with FLASH parameters are needed before the Fricke dosimetry can be used as primary standard in UHPDR electron beams. Such studies will be carried out by as part of work package 1 (WP 1) of UHDpulse."},
:properties {:color "yellow"}}
{:id #uuid "659b0db6-1445-4527-b359-a6a6fefc121a",
:page 10,
:position {:bounding {:x1 572.296875,
:y1 619.03125,
:x2 1040.96923828125,
:y2 693.546875,
:width 1111.181868533333,
:height 1481.5751794666667},
:rects ({:x1 594.640625,
:y1 619.03125,
:x2 1040.96923828125,
:y2 635.03125,
:width 1111.181868533333,
:height 1481.5751794666667}
{:x1 572.296875,
:y1 638.5,
:x2 1039.9124755859375,
:y2 654.5,
:width 1111.181868533333,
:height 1481.5751794666667}
{:x1 572.296875,
:y1 658.078125,
:x2 1040.937255859375,
:y2 674.078125,
:width 1111.181868533333,
:height 1481.5751794666667}
{:x1 572.296875,
:y1 677.546875,
:x2 759.1262817382812,
:y2 693.546875,
:width 1111.181868533333,
:height 1481.5751794666667}),
:page 10},
:content {:text "In addition, it is planned to explore beam current transformers(BCT), such as AC Current Transformer (ACCT) or Integrating Current Transformer (ICT). These devices are promising, even though they are not used in clinical settings. "},
:properties {:color "yellow"}}
{:id #uuid "659b1b51-bca4-40f3-aa05-fd34eb2af1ba",
:page 6,
:position {:bounding {:x1 62.640625,
:y1 1030.96875,
:x2 485.53228759765625,
:y2 1063.359375,
:width 992.1266683333332,
:height 1322.8349816666666},
:rects ({:x1 65.93588256835938,
:y1 1030.96875,
:x2 485.53228759765625,
:y2 1047.96875,
:width 992.1266683333332,
:height 1322.8349816666666}
{:x1 62.640625,
:y1 1048.359375,
:x2 122.56260681152344,
:y2 1063.359375,
:width 992.1266683333332,
:height 1322.8349816666666}),
:page 6},
:content {:text "nvestigating ion recombination in ionization chambers under such conditions"},
:properties {:color "yellow"}}],
2024-01-12 22:46:43 +00:00
:extra {:page 3}}