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Miriam Brosi 2024-01-13 14:20:41 +01:00
parent 9669bf1510
commit 3a7d08a85f
10 changed files with 47231 additions and 178 deletions

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- The principle of ionization chambers is based on two electrodes with an applied voltage to generate an electric field. Upon exposure to ionizing radiation, molecules in the chamber gas are ionized and excited, creating ion pairs in random thermal motion that are collected by the electrodes, and the charge can then be used to quantify the absorbed dose. The polarizing voltage applied over the chamber is typically high enough to collect all the produced ion pairs. However, at high dose rates, ion pairs may recombine before being collected by the electrodes. After a certain threshold of produced charge per unit time, the charge collection efficiency decreases with increasing DPP
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- If this is not sufficient to collect all ion pairs, the remaining loss in efficiency due to ion recombination can usually be corrected for using theoretical models from Boag et al.(59). However, for the UHDR beams used in FLASH-RT (DPP values in the order of Gy), these models are insufficient.
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- Small chambers (which are not recommended for reference dosimetry in currently existing dosimetry protocols) have been shown to require smaller recombination correction factors compared to larger chambers(60,61). This is consistent with Boag's theories, which state that ion recombination is proportional to the distance between the electrodes and inversely proportional to the strength of the electric fiel
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