diff --git a/emmy_noether/.~lock.53_05_en_elan_projectdescription_draft.rtf# b/emmy_noether/.~lock.53_05_en_elan_projectdescription_draft.rtf# index bac480f..6bd1371 100644 --- a/emmy_noether/.~lock.53_05_en_elan_projectdescription_draft.rtf# +++ b/emmy_noether/.~lock.53_05_en_elan_projectdescription_draft.rtf# @@ -1 +1 @@ -,mirbro,w-mirbro-pc-0,12.01.2024 00:50,file:///home/mirbro/.config/libreoffice/4; \ No newline at end of file +,mirbro,w-mirbro-pc-0,12.01.2024 00:54,file:///home/mirbro/.config/libreoffice/4; \ No newline at end of file diff --git a/emmy_noether/53_05_en_elan_projectdescription_draft.rtf b/emmy_noether/53_05_en_elan_projectdescription_draft.rtf index ee48804..8027a70 100644 --- a/emmy_noether/53_05_en_elan_projectdescription_draft.rtf +++ b/emmy_noether/53_05_en_elan_projectdescription_draft.rtf @@ -478,7 +478,7 @@ {\listlevel\levelnfc255\leveljc0\levelstartat1\levelfollow2{\leveltext \'00;}{\levelnumbers;}\fi0\li0} {\listlevel\levelnfc255\leveljc0\levelstartat1\levelfollow2{\leveltext \'00;}{\levelnumbers;}\fi0\li0} {\listlevel\levelnfc255\leveljc0\levelstartat1\levelfollow2{\leveltext \'00;}{\levelnumbers;}\fi0\li0}\listid2} -}{\listoverridetable{\listoverride\listid1\listoverridecount0\ls1}{\listoverride\listid2\listoverridecount0\ls2}}{\*\generator LibreOffice/7.3.7.2$Linux_X86_64 LibreOffice_project/30$Build-2}{\info{\*\company DFG}{\author strauss}{\creatim\yr2019\mo1\dy21\hr11\min46}{\revtim\yr2024\mo1\dy12\hr0\min49}{\printim\yr2011\mo7\dy6\hr8\min48}}{\*\userprops{\propname Operator}\proptype30{\staticval westermann}}\deftab708\deftab708\deftab708\deftab708\deftab708 +}{\listoverridetable{\listoverride\listid1\listoverridecount0\ls1}{\listoverride\listid2\listoverridecount0\ls2}}{\*\generator LibreOffice/7.3.7.2$Linux_X86_64 LibreOffice_project/30$Build-2}{\info{\*\company DFG}{\author strauss}{\creatim\yr2019\mo1\dy21\hr11\min46}{\revtim\yr2024\mo1\dy12\hr0\min54}{\printim\yr2011\mo7\dy6\hr8\min48}}{\*\userprops{\propname Operator}\proptype30{\staticval westermann}}\deftab708\deftab708\deftab708\deftab708\deftab708 \hyphauto1\viewscale160 {\*\pgdsctbl {\pgdsc0\pgdscuse451\pgwsxn11906\pghsxn16838\marglsxn1418\margrsxn1134\margtsxn1418\headery709\margbsxn851{\header\pard\plain \s436\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tqc\tx4536\tqr\tx9072\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\tqc\tx4536\tqr\tx9072\li0\ri0\lin0\rin0\fi0{\rtlch\af16\afs17 \ltrch\lang2057\loch\fs17\lang2057\b0\loch @@ -716,6 +716,10 @@ Also much more effective and less treatment time necessary per patient\u8230\'85 The underlying mechanism behind FLASH radiotherapy is believed to involve the generation of reactive oxygen species (ROS) within tumor cells, which are more susceptible to damage from high doses of ionizing radiation than healthy tissues. The rapid delivery of these pulses allows for minimal ROS production in normal tissue, reducing the risk of side effects and enhancing treatment tolerance. } \par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch +\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch +Bisher noch nicht in klinischer anwendung, da so wie die kurzen pusle mit hoher dose rate die biologischen prozesse \u228\'e4ndern (zum vorteil) so anderen sie auch die prozesse in der detektion. Ion.recombination strongly increased\u8230\'85...but also normally cw gemessen und nun pl\u246\'f6tzlich zeitaufgel\u246\'f6st, braucht auch so f\u252\'fcr diagnostic einiges anpassung, wie auslese...} +\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch + \par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch Problems: short pulses + intenstiy / high dose -> resulting high dose rate make dose measurement difficult as different typical dosimetry technics show a deviation from the necessary linear detection efficiency. Including the primary standard of dose absorbed to water via Fricke dosimetry. Furthermore, for most standard medical accelerators these beam conditions are challenging to impossible to archive, requiring substantial improvement or the development of new dedicated FLASH accelerators. Additionally to the possibility to generate beams for FLASH RT also the diagnostic and simulation for these type of beams need to be adjusted and brought up to the high level necessary for clinical appllication\u8230\'85} \par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch