168 lines
6.7 KiB
Text
168 lines
6.7 KiB
Text
- flash = high dose rights per pusle (and short bursts) -> similar to high single bunch currents (special dynamcis which I studied)
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-> metrological challenges -> I know.
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coming from beam diagnostics?
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- precise current measurement with BCTs /ICT/ACCT.
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(weird question can we use synchrotron light? from a bend of the electron transfer line, at least relative calibration? fast optical diode?)
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---------------
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KIT advantages
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laser based sources -> one is coming.
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- could we couple out electron bunches at c-start? at different times after injection -> different bunch length, so could do can of effect of bunch length?
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- the virtual diagnostic for flute (indicates that good knowledge of accelerator) could be helpful to adjust machine settings according to measured radiation doses or similar?
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- flute not high charge but kurze pulse! grenze für kurze pulse in dosimetry pushen?
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- ATP
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- HEIKA?
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- neugebackenes Zentrum HealthTechnologies
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----------------
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Questions.
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- flash is all about particle beams right?, so low alpha at 2.5GeV does not help even so it might provide short x ray pulses? -> also x-ray flash (x-ray energy conventional therapy >=6MeV, but only 100keV at ESRF s41571-022-00697-z-1_overview_FLASH_therapy.pdf, KARA kritische Energy bei 2.5GeV nur 6.2keV, vlt bis 50keV etwas fluss?)
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- can we use electron pulses from flute or is only light possible?
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- what where the electron energies for flash, does flute/c-start fit?
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- when is cstart build?
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- how high is VHEE radiotherapy? (very high energy electron) ( earlier below 50MeV, proposed up to 200MeV?)
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In the framework of the European Metrology Programme for Innovation and Research (EMPIR),
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the project “Metrology for advanced radiotherapy using particle beams with ultra-high pulse dose rates
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(UHDpulse)” has started in September 2019 until 2023, also funded by European Union’s Horizon 2020 research and innovation programme
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more questions
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-max beam transverse size flute vs what is needed for (microbeam) RT?
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-possibility to have adjustable divergence in e beam at exit to make bigger spot on target?
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-flute instrumentation, where along flute is YAG:Ce screen?
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what does modality mean?:
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-a particular way of doing or experiencing something:
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ex. A variety of modalities of communication can be used to transmit health warnings to the public.
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- a type of treatment for a disease or medical condition:
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ex. Examples of medical modalities include chemotherapy, radiotherapy, and drug therapy.
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------------------------
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IDEAs
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(pulsed diagnostics and dosimetry on particle accelerators towards flash/radiation therapy applications?)
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(grenze für kurze pulse in dosimetry pushen?)
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non-linear optics and collective effects in accelerator generated temporally and/or spatially structured RT beams
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advanced beam-dynamics for shaped/structured beams for accelerator based RT
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Beam shaping for accelerator radiotherapy BESART
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RAD: Radiotherapy Accelerator Dynamics
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?shaped beams for acc RT?
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?Modulate?
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ModBeams? modulated beam
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complex dynamics of structured beams for advanced radiation therapy
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sabart - structured accelerator beams for advanced radiotherapy
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sebart - structured electron beams for accelerator radiotherapy
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accelerator dynamics for RT (ADRT)
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DART Dynamcis in Accelerators for RT
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DiAtaRT/DIATART Dynamcis in Accelerators towards advanced RT
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DiAfaRT/DIAFART Dynamcis in Accelerators for advanced RT
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DIAFORTE dynamcis in accelerators FOr RadioThErapy (Enhancements)
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DISABFART/DISABTART dynamics in shaped/structured accelerator beams for/towards advanced RT
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novel advanced RT modalities
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RADIANT: Radiotherapy Accelerator Dynamics In Advanced Novel The
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DiaRT Dynamcis in Accelerators (for) RT
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DIABART Dynamcis in Accelerator based advanced RT
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DiaRTYM Dynamics In Accelerator RadiotherapY Modalities
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MADAME modulated beams through advanced dynamics in accelerators by mastering electron beams
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MADAMRT modulated advanced dynamics for accelerator modalities in RT (in<->for)
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Mobadyn Modulated beams trough advanced dynamics
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ADiSBmfAbaRT advanced dynamics in structured beam modalities for accelerator based advanced RT
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BRAD BEST RT trough advanced dynamcis
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dynamics in structured beams for advanced accelerator based radiation therapy
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START structured beams for advanced/Accelerator RT
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research for ....
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----------
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TODO: microbeams only x-ray? only at 3rd generation lightsources as parallel beam with low emittance necessary??? (see ESRF https://www.esrf.fr/home/UsersAndScience/Experiments/CBS/ID17/mrt-1.html) -> KARA???
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What about not generating with mask but with structured electron beam
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can electrons be used in MRT (microbeam radiotherapy)?
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pulse charakteristik bunch strukture, mikro beams
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probleme auch pulse längen messung nicht nur charge
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räumliches pattern wichtig (mikrobeams) als weiterer schwerpunkt zu flash (was nur kurz sagt)
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spacial light modulator aber space ladung effecte
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aber spatial light modulator kann auch die unebenheit der kathode compensieren oder für bessere (transveres) flat top pulse sorgen die hilfreich für berechnung von spacecharge zeug sein kann.
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Experiment
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vorher messen und dann was passiert wenn durch wasser durch
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Simulations code erweitern wenn sie durch wasser durch fliegen
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Später als perspektive helium ion, kurzpulse dosimetrie bei ionen heidelberg.
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-Anke altes paper blei (beta)funktionen tracken bis fenster und weiter
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kovarianz matrizen für transport außerhalb vakuum, fluka für interaktion (streuprozesse)
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beamlets beeinflussen sich gegenseitig,
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wurde schon angewand bei MICE and am CERN
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Muss wisse dass ich weis was ich machen will, und überzeugen dass ich das handwerkzeug habe.
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Was brauch ich für kompetenzen.
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Simulaten als auch Experimentaler, 2phd und 1 postdoc + masteranden
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eigene arbeitspackete aber auch lehr und admin tätigkeiten.
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lehrveranstalung muss vorher absprechen
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gemeinsamer studiengang mit kit und heidelberg und etechnik und medizin
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Für geld, doktorand in ingenieur bekommen 100%
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hinweise dass mikro beams rolle spielen in strahlen terapie
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verträglicher machen /schonender
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nicht erforscht, wie pattern sind, also flexibilität welche!
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wie bekomme ich die in geweben, den weg simulieren, wie erzeugen, spatial light modulator
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wie testen, und messen
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welche pattern dann von medicine vorgegebe, bereit sind für alles
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mit detektor menschen wie husemann, strahlenhart, detector test mit mehrern pixel auf einmal als spin off!
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im material, scattering,
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hohe space charge, weil mikro bunches,
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hohe energie
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für verschieden energien machen (5 und 50MeV)
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oder plasma mit energy spread, schlechtere qualität
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bei ionen vlt mit maske, sonst wirds schwer
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kooperations partner aufführen, heidelberg, kit (Healthtech)
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konzept mit ein paar punkten auf folie dann mit anke und später mit anderen leuten wie medizinern diskutieren.....
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