Antrag/emmy_noether/53_05_en_elan_projectdescription_draft.rtf
2024-01-12 00:55:24 +01:00

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281 KiB
Text

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S}{\loch\lang2057\loch
tructured }{\loch\lang2057\loch
B}{\loch\lang2057\loch
eams for }{\loch\lang2057\loch
A}{\loch\lang2057\loch
dvanced }{\loch\lang2057\loch
A}{\loch\lang2057\loch
ccelerator based }{\loch\lang2057\loch
R}{\loch\lang2057\loch
adiation }{\loch\lang2057\loch
T}{\loch\lang2057\loch
herapy}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\brdrb\brdrs\brdrw10\brdrcf1\brsp20\rtlch\afs22 \ltrch\lang2057\loch\lang2057\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs22 \ltrch\lang2057\loch\lang2057\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang2057\loch
{\*\bkmkstart _Toc2867618961}{\*\bkmkstart _Toc283039039}{\*\bkmkstart _Toc283017236}{\*\bkmkstart _Toc283038945}{\*\bkmkstart _Toc283017362}{\*\bkmkend _Toc2867618961}{\*\bkmkend _Toc283039039}{\*\bkmkend _Toc283017236}{\*\bkmkend _Toc283038945}{\*\bkmkend _Toc283017362}Project Description}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\fs18\lang2057\i\b0\loch
Sections 1-3 must not exceed 17 pages in total.}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\af16\afs22 \ltrch\lang2057\loch\lang2057\b0\loch
\par \pard\plain \s1\rtlch\af13\afs24\alang1025\ab \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx432\hyphpar0\faauto\li432\ri0\lin432\rin0\fi-432\keepn\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\loch\fs22\i0\b 1\tab}\ilvl0\ls1 \li864\ri0\lin864\rin0\fi-432\sl288\slmult1\tx432{\loch\lang1033\loch
Starting Point}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang2057\loch
State of the art and preliminary work}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch
Radiotherapy }{\loch\lang1033\b0\loch
(RT) }{\loch\lang1033\b0\loch
has been }{\loch\lang1033\b0\loch
continuously }{\loch\lang1033\b0\loch
a very valuable tool in cancer treatment and with the significant advances in the field }{\loch\lang1033\b0\loch
in}{\loch\lang1033\b0\loch
}{\loch\lang1033\b0\loch
over the years, RT}{\loch\lang1033\b0\loch
promises to contribute even more }{\loch\lang1033\b0\loch
towards }{\loch\lang1033\b0\loch
a }{\loch\lang1033\b0\loch
successful and well tolerable treatment of cancer by reducing side effects while maintaining or even enhancing treatment efficacy in the future and improving the quality of life of the patients. }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch
In Europe, radiotherapy is recommended as part of the treatment plan for around 50% of cancer patients}{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate -2017370845}\loch\lang1033\b0\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql\loch{\rtlch\ai0\ab0\afs24\af18\alang1081 \ltrch\langfe2052\lang1033\hich\af3\loch\fs20\scaps0\caps0\accnone\cf0\lang1033\expnd0\expndtw0\kerning1\shad0\outl0\i0\strike0\ulnone\ulc0\b0\charscalex100\f3\dbch\af20\langfe2052\loch
Josep M. Borras, Yolande Lievens & Cai Grau (2015) The need for radiotherapy in Europe in 2020: Not only data but also a cancer plan, Acta Oncologica, 54:9, 1268-1274, DOI: 10.3109/0284186X.2015.1062139 }}}{\loch\lang1033\b0\loch
.}{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate -2017371356}\loch\cf20\lang1033\b0\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql\loch{\rtlch\ai0\ab0\afs24\af18\alang1081 \ltrch\langfe2052\lang1033\hich\af3\loch\fs20\scaps0\caps0\accnone\cf0\lang1033\expnd0\expndtw0\kerning1\shad0\outl0\i0\strike0\ulnone\ulc0\b0\charscalex100\f3\dbch\af20\langfe2052\loch
In the EU, more than 3,000 medical accelerators are in use for RT, and in}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\alang1081\af18\afs24\ab0\ai0 \ltrch\lang1033\langfe2052\hich\af3\loch\cf0\f3\charscalex100\b0\ulnone\ulc0\strike0\i0\outl0\shad0\kerning1\expnd0\expndtw0\lang1033\accnone\scaps0\caps0\fs20\dbch\langfe2052\af20\loch
Germany, more than 250,000 patients receive RT as part of their cancer treatment each year.}}}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch
Scientific and technological advances in a broad spectrum of scientific disciplines are an important cornerstone for developments }{\loch\lang1033\b0\loch
in radiotherapy due to the high performance requirements on the used technologies. Radiotherapy uses ionizing radiation to damage the DNA within the tumor cells, which prevents the cells from reproducing and eventually leads to their death. One common approach employs high-energy beams of particles or x-rays to irradiate the cancer cells and shrink or destroy the tumors. This non-invasive, targeted approach focuses on delivering a precise and targeted dose of ionizing radiation directly to the affected area, minimizing damage to healthy tissues while effectively treating the selected area. }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch
As still small areas of healthy tissue is irradiated in order to ensure the treatment of all cancerous cells, }{\loch\lang1033\b0\loch
an accurate control of the }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
dose rate }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
is required}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
to keep a balance }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
between tumor control and normal tissue tolerance. }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
The }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
range }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
between}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
radiation doses that effectively destroy cancer cells while }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
only causing minimal }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
damage to healthy tissues and organs }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
is called the therapeutic window.}{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate -2017370960}\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql\loch{\rtlch\af18\ab0\afs24\ai0\alang1081 \ltrch\langfe2052\lang1033\hich\af3\loch\strike0\i0\accnone\scaps0\caps0\b0\cf1\charscalex100\fs20\lang1033\outl0\f3\expnd0\expndtw0\ulnone\ulc0\kerning0\shad0\dbch\langfe2052\af21\loch
. The therapeutic}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\alang1081\ai0\afs24\ab0\af18 \ltrch\lang1033\langfe2052\hich\af3\loch\shad0\kerning0\ulnone\ulc0\expnd0\expndtw0\f3\outl0\lang1033\fs20\charscalex100\cf1\b0\scaps0\caps0\accnone\i0\strike0\dbch\af21\langfe2052\loch
window is the dose region between the normal tissue complication}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\af18\ab0\afs24\ai0\alang1081 \ltrch\langfe2052\lang1033\hich\af3\loch\strike0\i0\accnone\scaps0\caps0\b0\cf1\charscalex100\fs20\lang1033\outl0\f3\expnd0\expndtw0\ulnone\ulc0\kerning0\shad0\dbch\langfe2052\af21\loch
probability (NTCP) and the tumour control probability (TCP) curves}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\alang1081\ai0\afs24\ab0\af18 \ltrch\lang1033\langfe2052\hich\af3\loch\shad0\kerning0\ulnone\ulc0\expnd0\expndtw0\f3\outl0\lang1033\fs20\charscalex100\cf1\b0\scaps0\caps0\accnone\i0\strike0\dbch\af21\langfe2052\loch
(Fig. 1); \uc3 \u8220\'e2\'80\'9ctowards clinical FLASH\u8221\'e2\'80\'9d\uc1 }}}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
In conventional radiotherapy, t}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
his }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
requires a}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
carefully balancing }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
of }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
the number of fractions (dose sessions) and }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
the}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
dose per fraction to achieve optimal results }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
and avoiding}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
excessive harm to nearby healthy tissues. }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
A }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
widening }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
of }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
this window is }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
one of the }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
main goal}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
s}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
of radiotherapy research. }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
The external beam radiotherapy (EBRT) is based on particle accelerators to produce the high-energy beams, which can range from x-rays over electrons and protons to }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
helium and carbon}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
ions. The different beam types offer different advantages in their interaction with matter. Photon (x-ray) radiotherapy is the most common form and has been widely studied. }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
Beam e}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
nergies can range from low energies around 100 keV for superficial treatment up to energies as high as 4 to 25 MeV for treatments of }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
larger }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
tumors deep within the body. }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
More than 90% of radiotherapy patients receive high-energy X-rays produced by bremsstrahlung of electrons accelerated in linear accelerators. The direct usage of }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
electrons is limited }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
to more superficial treatments }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
as they only penetrate a few centimeters into tissue before losing energy. This makes electron radiotherapy particularly suitable for treating superficial or shallow tumors such as skin or lymphoma cancer, while sparing deeper organs. }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
Heavier particles like protons or ions }{\loch\lang1033\b0\loch
deposit most of their energy }{\loch\lang1033\b0\loch
immediately before}{\loch\lang1033\b0\loch
the end of their path through }{\loch\lang1033\b0\loch
the}{\loch\lang1033\b0\loch
tissue }{\loch\lang1033\b0\loch
(Bragg peak)}{\loch\lang1033\b0\loch
, resulting in reduced damage to healthy tissues }{\loch\lang1033\b0\loch
before and }{\loch\lang1033\b0\loch
beyond the target area. This makes proton }{\loch\lang1033\b0\loch
and ion}{\loch\lang1033\b0\loch
therapy particularly useful for treating deep tumors or those near critical structures. T}{\loch\lang1033\b0\loch
he requirements on stability and reproducibility of the accelerators providing the radiation beams are very high to ensure that the dose applied to the patient is within }{\loch\cf20\lang1033\b0\loch
1/5%}{\loch\lang1033\b0\loch
of the prescribed treatment dose. Therefore precise calibration and dosimetry measurements are required and national standards are defined. For conventional RT the }{\loch\lang1033\b0\loch
primary}{\loch\lang1033\b0\loch
standard }{\loch\lang1033\b0\loch
have been defined by several national metrology institutions. For conventional MeV electron beams the Fricke dosimetry method is used as primary standard for absorbed dose to water}{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate -1480499198}\loch\lang1033\b0\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql\loch{\rtlch\ai0\ab0\afs24\af18\alang1081 \ltrch\langfe2052\lang1033\hich\af3\loch\fs20\scaps0\caps0\accnone\cf0\lang1033\expnd0\expndtw0\kerning1\shad0\outl0\i0\strike0\ulnone\ulc0\b0\charscalex100\f3\dbch\af20\langfe2052\loch
@article\{H Feist_1989,}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\alang1081\af18\afs24\ab0\ai0 \ltrch\lang1033\langfe2052\hich\af3\loch\cf0\f3\charscalex100\b0\ulnone\ulc0\strike0\i0\outl0\shad0\kerning1\expnd0\expndtw0\lang1033\accnone\scaps0\caps0\fs20\dbch\langfe2052\af20\loch
doi = \{10.1088/0031-9155/34/12/009\},}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\ai0\ab0\afs24\af18\alang1081 \ltrch\langfe2052\lang1033\hich\af3\loch\fs20\scaps0\caps0\accnone\cf0\lang1033\expnd0\expndtw0\kerning1\shad0\outl0\i0\strike0\ulnone\ulc0\b0\charscalex100\f3\dbch\af20\langfe2052\loch
url = \{https://dx.doi.org/10.1088/0031-9155/34/12/009\},}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\alang1081\af18\afs24\ab0\ai0 \ltrch\lang1033\langfe2052\hich\af3\loch\cf0\f3\charscalex100\b0\ulnone\ulc0\strike0\i0\outl0\shad0\kerning1\expnd0\expndtw0\lang1033\accnone\scaps0\caps0\fs20\dbch\langfe2052\af20\loch
year = \{1989\},}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\ai0\ab0\afs24\af18\alang1081 \ltrch\langfe2052\lang1033\hich\af3\loch\fs20\scaps0\caps0\accnone\cf0\lang1033\expnd0\expndtw0\kerning1\shad0\outl0\i0\strike0\ulnone\ulc0\b0\charscalex100\f3\dbch\af20\langfe2052\loch
month = \{dec\},}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\alang1081\af18\afs24\ab0\ai0 \ltrch\lang1033\langfe2052\hich\af3\loch\cf0\f3\charscalex100\b0\ulnone\ulc0\strike0\i0\outl0\shad0\kerning1\expnd0\expndtw0\lang1033\accnone\scaps0\caps0\fs20\dbch\langfe2052\af20\loch
publisher = \{\},}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\ai0\ab0\afs24\af18\alang1081 \ltrch\langfe2052\lang1033\hich\af3\loch\fs20\scaps0\caps0\accnone\cf0\lang1033\expnd0\expndtw0\kerning1\shad0\outl0\i0\strike0\ulnone\ulc0\b0\charscalex100\f3\dbch\af20\langfe2052\loch
volume = \{34\},}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\alang1081\af18\afs24\ab0\ai0 \ltrch\lang1033\langfe2052\hich\af3\loch\cf0\f3\charscalex100\b0\ulnone\ulc0\strike0\i0\outl0\shad0\kerning1\expnd0\expndtw0\lang1033\accnone\scaps0\caps0\fs20\dbch\langfe2052\af20\loch
number = \{12\},}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\ai0\ab0\afs24\af18\alang1081 \ltrch\langfe2052\lang1033\hich\af3\loch\fs20\scaps0\caps0\accnone\cf0\lang1033\expnd0\expndtw0\kerning1\shad0\outl0\i0\strike0\ulnone\ulc0\b0\charscalex100\f3\dbch\af20\langfe2052\loch
pages = \{1863\},}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\alang1081\af18\afs24\ab0\ai0 \ltrch\lang1033\langfe2052\hich\af3\loch\cf0\f3\charscalex100\b0\ulnone\ulc0\strike0\i0\outl0\shad0\kerning1\expnd0\expndtw0\lang1033\accnone\scaps0\caps0\fs20\dbch\langfe2052\af20\loch
author = \{H Feist and U Muller\},}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\ai0\ab0\afs24\af18\alang1081 \ltrch\langfe2052\lang1033\hich\af3\loch\fs20\scaps0\caps0\accnone\cf0\lang1033\expnd0\expndtw0\kerning1\shad0\outl0\i0\strike0\ulnone\ulc0\b0\charscalex100\f3\dbch\af20\langfe2052\loch
title = \{Measurement of the total stopping power of 5.3 MeV electrons in polystyrene by means of electron beam absorption in ferrous sulphate solution\},}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\alang1081\af18\afs24\ab0\ai0 \ltrch\lang1033\langfe2052\hich\af3\loch\cf0\f3\charscalex100\b0\ulnone\ulc0\strike0\i0\outl0\shad0\kerning1\expnd0\expndtw0\lang1033\accnone\scaps0\caps0\fs20\dbch\langfe2052\af20\loch
journal = \{Physics in Medicine & Biology\},}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\ai0\ab0\afs24\af18\alang1081 \ltrch\langfe2052\lang1033\hich\af3\loch\fs20\scaps0\caps0\accnone\cf0\lang1033\expnd0\expndtw0\kerning1\shad0\outl0\i0\strike0\ulnone\ulc0\b0\charscalex100\f3\dbch\af20\langfe2052\loch
abstract = \{Describes how an experimental arrangement for the calibration of Fricke solution in terms of absorbed dose to water can be utilised to determine total, i.e. collisional and radiative, mass stopping power of high-energy electrons. As a first result the measurement of the total mass stopping power of polystyrene at about 5.3 MeV kinetic electron energy is presented in detail. Comparison of the obtained value with the corresponding result of recent theoretical computations shows agreement within the measurement uncertainty of about 1.2% (SD).\}}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\alang1081\af18\afs24\ab0\ai0 \ltrch\lang1033\langfe2052\hich\af3\loch\cf0\f3\charscalex100\b0\ulnone\ulc0\strike0\i0\outl0\shad0\kerning1\expnd0\expndtw0\lang1033\accnone\scaps0\caps0\fs20\dbch\langfe2052\af20\loch
\}}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\alang1023\af23 \ltrch\lang1023\langfe1023\hich\af3\loch\f3\fs24\b0\kerning0\lang1023\dbch\langfe1023\af22\loch
}}}{\loch\lang1033\b0\loch
. For proton therapy dosimetry, graphite calorimeters have been well established as primary standard level instruments.}{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate -1480499189}\loch\lang1033\b0\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql\loch{\rtlch\ai0\ab0\afs24\af18\alang1081 \ltrch\langfe2052\lang1033\hich\af3\loch\fs20\scaps0\caps0\accnone\cf0\lang1033\expnd0\expndtw0\kerning1\shad0\outl0\i0\strike0\ulnone\ulc0\b0\charscalex100\f3\dbch\af20\langfe2052\loch
@article\{Seuntjens_2009,}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\alang1081\af18\afs24\ab0\ai0 \ltrch\lang1033\langfe2052\hich\af3\loch\cf0\f3\charscalex100\b0\ulnone\ulc0\strike0\i0\outl0\shad0\kerning1\expnd0\expndtw0\lang1033\accnone\scaps0\caps0\fs20\dbch\langfe2052\af20\loch
doi = \{10.1088/0026-1394/46/2/S04\},}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\ai0\ab0\afs24\af18\alang1081 \ltrch\langfe2052\lang1033\hich\af3\loch\fs20\scaps0\caps0\accnone\cf0\lang1033\expnd0\expndtw0\kerning1\shad0\outl0\i0\strike0\ulnone\ulc0\b0\charscalex100\f3\dbch\af20\langfe2052\loch
url = \{https://dx.doi.org/10.1088/0026-1394/46/2/S04\},}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\alang1081\af18\afs24\ab0\ai0 \ltrch\lang1033\langfe2052\hich\af3\loch\cf0\f3\charscalex100\b0\ulnone\ulc0\strike0\i0\outl0\shad0\kerning1\expnd0\expndtw0\lang1033\accnone\scaps0\caps0\fs20\dbch\langfe2052\af20\loch
year = \{2009\},}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\ai0\ab0\afs24\af18\alang1081 \ltrch\langfe2052\lang1033\hich\af3\loch\fs20\scaps0\caps0\accnone\cf0\lang1033\expnd0\expndtw0\kerning1\shad0\outl0\i0\strike0\ulnone\ulc0\b0\charscalex100\f3\dbch\af20\langfe2052\loch
month = \{mar\},}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\alang1081\af18\afs24\ab0\ai0 \ltrch\lang1033\langfe2052\hich\af3\loch\cf0\f3\charscalex100\b0\ulnone\ulc0\strike0\i0\outl0\shad0\kerning1\expnd0\expndtw0\lang1033\accnone\scaps0\caps0\fs20\dbch\langfe2052\af20\loch
publisher = \{\},}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\ai0\ab0\afs24\af18\alang1081 \ltrch\langfe2052\lang1033\hich\af3\loch\fs20\scaps0\caps0\accnone\cf0\lang1033\expnd0\expndtw0\kerning1\shad0\outl0\i0\strike0\ulnone\ulc0\b0\charscalex100\f3\dbch\af20\langfe2052\loch
volume = \{46\},}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\alang1081\af18\afs24\ab0\ai0 \ltrch\lang1033\langfe2052\hich\af3\loch\cf0\f3\charscalex100\b0\ulnone\ulc0\strike0\i0\outl0\shad0\kerning1\expnd0\expndtw0\lang1033\accnone\scaps0\caps0\fs20\dbch\langfe2052\af20\loch
number = \{2\},}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\ai0\ab0\afs24\af18\alang1081 \ltrch\langfe2052\lang1033\hich\af3\loch\fs20\scaps0\caps0\accnone\cf0\lang1033\expnd0\expndtw0\kerning1\shad0\outl0\i0\strike0\ulnone\ulc0\b0\charscalex100\f3\dbch\af20\langfe2052\loch
pages = \{S39\},}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\alang1081\af18\afs24\ab0\ai0 \ltrch\lang1033\langfe2052\hich\af3\loch\cf0\f3\charscalex100\b0\ulnone\ulc0\strike0\i0\outl0\shad0\kerning1\expnd0\expndtw0\lang1033\accnone\scaps0\caps0\fs20\dbch\langfe2052\af20\loch
author = \{Jan Seuntjens and Simon Duane\},}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\ai0\ab0\afs24\af18\alang1081 \ltrch\langfe2052\lang1033\hich\af3\loch\fs20\scaps0\caps0\accnone\cf0\lang1033\expnd0\expndtw0\kerning1\shad0\outl0\i0\strike0\ulnone\ulc0\b0\charscalex100\f3\dbch\af20\langfe2052\loch
title = \{Photon absorbed dose standards\},}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\alang1081\af18\afs24\ab0\ai0 \ltrch\lang1033\langfe2052\hich\af3\loch\cf0\f3\charscalex100\b0\ulnone\ulc0\strike0\i0\outl0\shad0\kerning1\expnd0\expndtw0\lang1033\accnone\scaps0\caps0\fs20\dbch\langfe2052\af20\loch
journal = \{Metrologia\},}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\ai0\ab0\afs24\af18\alang1081 \ltrch\langfe2052\lang1033\hich\af3\loch\fs20\scaps0\caps0\accnone\cf0\lang1033\expnd0\expndtw0\kerning1\shad0\outl0\i0\strike0\ulnone\ulc0\b0\charscalex100\f3\dbch\af20\langfe2052\loch
abstract = \{In this review the current status of absorbed dose to water standards for high-energy photon beams (60Co\uc3 \u8212\'e2\'80\'9450\u8201\'e2\'80\'89MV nominal accelerating potential) is discussed. The review is focused on calorimeter-based absorbed dose standards for photon radiation therapy calibrations with typical dose rates of a few gray per minute. In addition, two alternative types of absorbed dose standards are also discussed. The overall uncertainty on measured dose to water in static reference fields is nowadays on the order of 0.4% to 0.5%. The components contributing to the uncertainty budgets are discussed. The discussed absorbed dose to water standards are expected to continue to have their place not only in the dissemination of absorbed dose to water but also in the determination of beam quality conversion factors essential in reference dosimetry in high-energy photon beams.\}\uc1 }\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\alang1081\af18\afs24\ab0\ai0 \ltrch\lang1033\langfe2052\hich\af3\loch\cf0\f3\charscalex100\b0\ulnone\ulc0\strike0\i0\outl0\shad0\kerning1\expnd0\expndtw0\lang1033\accnone\scaps0\caps0\fs20\dbch\langfe2052\af20\loch
\}}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\alang1023\af23 \ltrch\lang1023\langfe1023\hich\af3\loch\f3\fs24\b0\kerning0\lang1023\dbch\langfe1023\af22\loch
}}}{\loch\lang1033\b0\loch
}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch
A}{\loch\lang1033\b0\loch
dvancement}{\loch\lang1033\b0\loch
s}{\loch\lang1033\b0\loch
and new concepts of treatment }{\loch\lang1033\b0\loch
and beam }{\loch\lang1033\b0\loch
modalities in }{\loch\lang1033\b0\loch
radiotherapy lead to }{\loch\lang1033\b0\loch
increasing requirements on }{\loch\lang1033\b0\loch
dosimetry and}{\loch\lang1033\b0\loch
}{\loch\lang1033\b0\loch
as well as on the diagnostics and understanding of the beam dynamics in the }{\loch\lang1033\b0\loch
accelerator}{\loch\lang1033\b0\loch
s used for beam generation. Especially for new approaches including either temporally or spatially modulated beams, new effects might need to be considered in the examination and simulation of the beams and their generation. T}{\loch\cf20\lang1033\b0\loch
wo ne}{\loch\lang1033\b0\loch
w approaches to radiotherapy have received considerable attention in the last years and are investigated in preclinical trials. }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch
--------}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch
FLASH RT is a novel approach focuses on delivering very high doses in an ultra-short time frame, typically within milliseconds or less. This technique aims to exploit the unique properties of these short pulses to enhance tumor cell killing while minimizing damage to surrounding healthy tissues. }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch
Number???? >=40Gy/s with pulse length <500ms and total doses of >= 10Gy opposed to 1.8-2Gy per fraction in 30 fractions with a dose rate of 0.2-20Gy/min. }{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate -1480499167}\loch\lang1033\b0\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql\loch{\rtlch\ai0\ab0\afs24\af18\alang1081 \ltrch\langfe2052\lang1033\hich\af3\loch\fs20\scaps0\caps0\accnone\cf0\lang1033\expnd0\expndtw0\kerning1\shad0\outl0\i0\strike0\ulnone\ulc0\b0\charscalex100\f3\dbch\af20\langfe2052\loch
Paper GSI}}}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch
FLASH effect\u8230\'85.very short exposure time with high dose, increases significantly therapeutic window\u8230\'85.}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch
Reported that Works for all typical radiation modalities used in RT}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch
The primary advantage of FLASH radiotherapy is its ability to achieve significantly higher doses than conventional radiation therapy without causing severe side effects, such as acute normal tissue reactions or long-term complications. This increased efficacy may lead to improved treatment outcomes and reduced overall toxicity for patients with various types of cancer.}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch
Also much more effective and less treatment time necessary per patient\u8230\'85.}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch
The underlying mechanism behind FLASH radiotherapy is believed to involve the generation of reactive oxygen species (ROS) within tumor cells, which are more susceptible to damage from high doses of ionizing radiation than healthy tissues. The rapid delivery of these pulses allows for minimal ROS production in normal tissue, reducing the risk of side effects and enhancing treatment tolerance. }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch
Bisher noch nicht in klinischer anwendung, da so wie die kurzen pusle mit hoher dose rate die biologischen prozesse \u228\'e4ndern (zum vorteil) so anderen sie auch die prozesse in der detektion. Ion.recombination strongly increased\u8230\'85...but also normally cw gemessen und nun pl\u246\'f6tzlich zeitaufgel\u246\'f6st, braucht auch so f\u252\'fcr diagnostic einiges anpassung, wie auslese...}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch
Problems: short pulses + intenstiy / high dose -> resulting high dose rate make dose measurement difficult as different typical dosimetry technics show a deviation from the necessary linear detection efficiency. Including the primary standard of dose absorbed to water via Fricke dosimetry. Furthermore, for most standard medical accelerators these beam conditions are challenging to impossible to archive, requiring substantial improvement or the development of new dedicated FLASH accelerators. Additionally to the possibility to generate beams for FLASH RT also the diagnostic and simulation for these type of beams need to be adjusted and brought up to the high level necessary for clinical appllication\u8230\'85}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
FLASH}{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate 1203850184}\loch\lang1033\b0\sl240\slmult1\loch{\rtlch\af18\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
FLASH Radiotherapy is a novel approach to cancer treatment that involves delivering very high doses of ionizing radiation in an ultra-short time frame, typically within milliseconds or less. This technique aims to exploit the unique properties of these short pulses to enhance tumor cell killing while minimizing damage to surrounding healthy tissues.}\par\loch\sl240\slmult1{\rtlch\alang1023\af23 \ltrch\lang1023\langfe1023\hich\af3\loch\f3\fs24\b0\kerning0\lang1023\dbch\langfe1023\af22\loch
}\par\loch\sl240\slmult1{\rtlch\af18\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
The primary advantage of FLASH radiotherapy is its ability to achieve significantly higher doses than conventional radiation therapy without causing severe side effects, such as acute normal tissue reactions or long-term complications. This increased efficacy may lead to improved treatment outcomes and reduced overall toxicity for patients with various types of cancer.}\par\loch\sl240\slmult1{\rtlch\alang1023\af23 \ltrch\lang1023\langfe1023\hich\af3\loch\f3\fs24\b0\kerning0\lang1023\dbch\langfe1023\af22\loch
}\par\loch\sl240\slmult1{\rtlch\af18\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
The underlying mechanism behind FLASH radiotherapy is believed to involve the generation of reactive oxygen species (ROS) within tumor cells, which are more susceptible to damage from high doses of ionizing radiation than healthy tissues. The rapid delivery of these pulses allows for minimal ROS production in normal tissue, reducing the risk of side effects and enhancing treatment tolerance.}\par\loch\sl240\slmult1{\rtlch\alang1023\af23 \ltrch\lang1023\langfe1023\hich\af3\loch\f3\fs24\b0\kerning0\lang1023\dbch\langfe1023\af22\loch
}\par\loch\sl240\slmult1{\rtlch\af18\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
FLASH radiotherapy is still under investigation, with ongoing clinical trials assessing its safety and efficacy across different cancer types. If proven effective, this innovative approach could revolutionize radiation therapy by offering a more targeted and less toxic method for treating various forms of cancer.}}}{\loch\lang1033\b0\loch
auch offene punkte?/challanges dosimetry, accuary but also biologically }{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate -2017371354}\loch\lang1033\b0\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql\loch{\rtlch\alang1081\ai0\ab0\afs24\af18 \ltrch\langfe2052\lang1033\hich\af3\loch\scaps0\caps0\accnone\cf0\lang1033\expnd0\expndtw0\kerning1\shad0\outl0\i0\strike0\ulnone\ulc0\b0\charscalex100\fs20\f3\dbch\af20\langfe2052\loch
A prerequisite for systematically investigating the}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\alang1081\af18\afs24\ab0\ai0 \ltrch\lang1033\langfe2052\hich\af3\loch\cf0\f3\fs20\charscalex100\b0\ulnone\ulc0\strike0\i0\outl0\shad0\kerning1\expnd0\expndtw0\lang1033\accnone\scaps0\caps0\dbch\langfe2052\af20\loch
biological effects of uHDR is a sound understanding and control of the challenging short-pulse}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\alang1081\ai0\ab0\afs24\af18 \ltrch\langfe2052\lang1033\hich\af3\loch\scaps0\caps0\accnone\cf0\lang1033\expnd0\expndtw0\kerning1\shad0\outl0\i0\strike0\ulnone\ulc0\b0\charscalex100\fs20\f3\dbch\af20\langfe2052\loch
dynamics for ions, electrons, and photons. Short pulses and variable repetition rates down to}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\alang1081\af18\afs24\ab0\ai0 \ltrch\lang1033\langfe2052\hich\af3\loch\cf0\f3\fs20\charscalex100\b0\ulnone\ulc0\strike0\i0\outl0\shad0\kerning1\expnd0\expndtw0\lang1033\accnone\scaps0\caps0\dbch\langfe2052\af20\loch
micro-beams and micro-structures in the GHz and THz range have to be delivered reliably and}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\alang1081\ai0\ab0\afs24\af18 \ltrch\langfe2052\lang1033\hich\af3\loch\scaps0\caps0\accnone\cf0\lang1033\expnd0\expndtw0\kerning1\shad0\outl0\i0\strike0\ulnone\ulc0\b0\charscalex100\fs20\f3\dbch\af20\langfe2052\loch
reproducibly. This module deals with the experimental and theoretical prerequisites (non-}\par\loch\ltrpar\aspalpha\li0\ri0\lin0\rin0\fi0\sb0\sa0\sl240\slmult1\ql{\rtlch\alang1081\af18\afs24\ab0\ai0 \ltrch\lang1033\langfe2052\hich\af3\loch\cf0\f3\fs20\charscalex100\b0\ulnone\ulc0\strike0\i0\outl0\shad0\kerning1\expnd0\expndtw0\lang1033\accnone\scaps0\caps0\dbch\langfe2052\af20\loch
equilibrium beam physics, instrumentation, control). H}}}{\loch\lang1033\b0\loch
}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0
}{\loch\lang1033\b0\loch
requirements on stability and metrology of the used beams not yet fulfilled}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0
\u9654\'3f }{\loch\lang1033\b0\loch
primary standard of standard particle RT not directly applicable}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0
\u9654\'3f }{\loch\lang1033\b0\loch
discrepancy observed between measured dose and simulated}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0
\u9654\'3f }{\loch\lang1033\b0\loch
non-linearity in detectors at ultra-high dose rates (e.g. high ion recombination rate)}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0
\u8594\'3f }{\loch\lang1033\b0\loch
improved by UHDpulse project, still open questions}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0
\u9654\'3f }{\loch\lang1033\b0\loch
simulation of dose does in most cases do not consider interaction between beam particles}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0
\u9654\'3f }{\loch\lang1033\b0\loch
most diagnostic focuses on beam outside accelerator, potential of fast and accurate}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch
accelerator diagnostic not fully exploited (e.g. shot by shot charge, position, size, ...}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch
measurements)}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0
\u9654\'3f }{\loch\lang1033\b0\loch
optimal parameters such as pulse duration, intensity and energy not yet medically clear}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0
\u9654\'3f }{\loch\lang1033\b0\loch
input to possible parameter areas, that can be provided reliably by accelerators needed}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0
\u9654\'3f }{\loch\lang1033\b0\loch
new accelerator types (e.g. laser-based ones for higher energies) bring also different beam}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch
dynamic effects to be considered, such as high energy spread, shot-to-shot variation, ...}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch
, und MRT here erkl\u228\'e4ren }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch
auch offene punkte}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch
Spatially structured RT}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0
\u9654\'3f }{\loch\lang1033\b0\loch
Microbeam RT mainly studied with x-rays but similar potential for particle beams as}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch
demonstrated with GRID therapy}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0
\u9654\'3f }{\loch\lang1033\b0\loch
modulation done mostly close to target}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0
\u9654\'3f }{\loch\lang1033\b0\loch
spatially modulated beams (non-Gaussian dose distribution) relevant to accommodate}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch
either irregular/uneven patient surfaces (e.g. electron conformal therapy ECT) or achieve}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch
homogeneous dose distributions}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0
\u9654\'3f }{\loch\lang1033\b0\loch
mostly handled by scanning, masks/collimators or bolus ECT}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch
General}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0
\u9654\'3f }{\loch\lang1033\b0\loch
no interaction between beam particles considered in most simulations (e.g. FLUKA,}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch
EGSnrc, BDSIM with Geant4)}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0
\u9654\'3f }{\loch\lang1033\b0\loch
OPAL does include 3D space charge, seems to mainly be used for proton therapy}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0
\u8658\'3f }{\loch\lang1033\b0\loch
Little to no mentioning of consideration of collective effects, which (from accelerator physics}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch
point of view) is expected to play an increasing role with decreasing pulse length and increasing}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch
pulse intensity, as well as with spatial structuring of the beam.}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch
Dann daraus basierend offene anforderungen an accelerator knowledge}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch
complex dynamics, collective effects, but also diagnostics for ?quality assurance?}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
Accelerator, Linac}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
beam dynamic, }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
collective effects, space charge\u8230\'85}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
explanation }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- two promising developments in recent years:}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- encouraging results with very short, high dose beams (FLASH RT)}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- recent further development of spatially fractionated RT towards Microbeam Radiation}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
Therapy (MRT)}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- both show improved sparing of healthy tissue and reduction of secondary cancer also}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
increasingly important due to increase in overall life expectancy}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- both are dependent on the use of particle accelerator facilities}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- for FLASH: to achieve the required intensity in short pulses, e.g. linear accelerators for}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
electron FLASH RT}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- for MRT: in case of x-ray beams, a high brilliant synchrotron light sources are required to}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
provide sufficiently parallel propagating Microbeams}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- very high requirements on stability and metrology of the used beams}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- medical accelerators are tailored to the specific application and need to be rather simple to run without to much maintenance, continuously in the day to day operation.}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- new beam modalities such as FLASH and micro-beam therapy have higher requirements on accelerators/source, therefore need to be tested at accelerator research facilities to define/map/study the most suitable parameter set?? before being implemented in a clinical setting}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- While research accelerators are more complex they, at the same time, provide much more flexibility and a higher degree of instrumentation}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- additionally profit (that they are much more characterized)?/ (from possibility for extensive studies) with regards to more complex beam dynamic effects which become more and more relevant with the push for more complex beam modalities, like shorter pulses (FLASH) or spatially structured beams}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- here I can contribute with my experience and research in ...}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
Me:}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- experience in longitudinal as well as transverse collective effects and instabilities}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
influencing the electron bunch shape in all dimensions}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- in general, investigating phenomena occurring under extreme operation modes, e.g. high}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
charge, small transverse bunch-size, short bunch-length, sub-structures, ...}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- on rings but focused on single bunch effects transferrable to linacs}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- simulations of non-linear optics and beam dynamics, collective effects}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- extensive experimental studies and measurements}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- used diagnostics: electron-beam based as well as synchrotron-radiation based (e.g. THz-Schottky diode detectors...)}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
as well as improved and further-developed diagnostic methods}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- data analysis of complex, big datasets with, among others, Python and HPC (high}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
performance computing}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- involve in development and benchmarking/test of new simulation, vlasov-fokker-planck solver based on charge distribution in longitudinal phase-space }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s1\rtlch\af13\afs24\alang1025\ab \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx432\hyphpar0\faauto\li432\ri0\lin432\rin0\fi-432\keepn\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\loch\fs22\i0\b 2\tab}\ilvl0\ls1 \li864\ri0\lin864\rin0\fi-432\sl288\slmult1\tx432{\loch\lang1033\loch
{\*\bkmkstart _Toc286761896}{\*\bkmkstart _Toc294157993}{\*\bkmkstart _Toc286908237}{\*\bkmkend _Toc286761896}{\*\bkmkend _Toc294157993}{\*\bkmkend _Toc286908237}Objectives and work programme}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch\lang1033\b0\loch
\par \pard\plain \s2\rtlch\af16\afs20\alang1025\ai\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx576\hyphpar0\faauto\li576\ri0\lin576\rin0\fi-576\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 2.1\tab}\ilvl1\ls1 \li1152\ri0\lin1152\rin0\fi-576\sl288\slmult1\tx576{\loch
{\*\bkmkstart _Toc2869082371}{\*\bkmkstart _Toc2941579931}{\*\bkmkstart _Toc2867618962}{\*\bkmkend _Toc2869082371}{\*\bkmkend _Toc2941579931}{\*\bkmkend _Toc2867618962}Anticipated total duration of the project}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
[Text] 6 years}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s2\rtlch\af16\afs20\alang1025\ai\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx576\hyphpar0\faauto\li576\ri0\lin576\rin0\fi-576\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 2.2\tab}\ilvl1\ls1 \li1152\ri0\lin1152\rin0\fi-576\sl288\slmult1\tx576{\loch
Objectives}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
[Text]Motivation:}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
The present advances in accelerator based RT, like FLASH RT or Microbeam RT, lead to}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
operation parameters of the used accelerators that can not anymore be described by simple}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
linear optics and beam dynamics. Instead, due to the development towards higher intensity}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
combined with shorter pulse lengths and transverse modulations, the consideration of}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
non-linear and complex optics as well as beam dynamics influenced by collective effects}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
becomes necessary for accelerator RT sources.}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
Further closing the gap between accelerator science and medical physics from the accelerator}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
side is an important step and will help in paving the way towards accurate predictability,}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
diagnostic and metrology of advanced RT with particle accelerators.}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
Goals:}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- improve predictability of RT beam properties on target by improving understanding of}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
dynamic in short and/or spatially structured RT beams (!!!spatially structured can be microbeams but also just not round/gaussian beams but more like flat, or narrow, or double peaked, any structure actually that can survive the path through accelerator/be formed at the end of accelerator!!)}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- study from accelerator point of view the beam dynamics effects relevant in the generation}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
of such beams as well as the diagnostic to reliably deliver the requested conditions}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- provide start-to-end simulations of the dynamic of RT beams, from inside the accelerator}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
through the air into the target by combining beam dynamics, beam-matter interaction and}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
collective effects simulations}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- predicting the temporal and spatial shape of each individual RT pulse at any point on the}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
way up to the target inside the patient}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
The goal is, by extending the calculation of these effects beyond the accelerator as a first step,}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
to make the prediction of the resulting spatial distribution on target possible. And as a second}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
step, it might allow to consider effects of the beam transport already during the generation of}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
the beam.}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
Aiming towards the generation of a spatial distribution which preemptively compensates for the}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
expected changes, possibly allowing arbitrary user-definable final distributions.}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s2\rtlch\af16\afs20\alang1025\ai\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx576\hyphpar0\faauto\li576\ri0\lin576\rin0\fi-576\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 2.3\tab}\ilvl1\ls1 \li1152\ri0\lin1152\rin0\fi-576\sl288\slmult1\tx576{\loch
Work programme incl. proposed research methods}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
Theoretical work:}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- literature research of models and methods to propagate structured radiation beams though air and matter, starting from e.g. GEANT4, BDSIM, EGSnrc (with BEAMnrc), ...}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- investigate evolution of different temporally and spatially structured radiation beams passing through matter, quantify deterioration of initial structuring based on path length in different materials and initial dimensions and size of structuring (based on requirements in FLASH and microbeam RT)}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- literature research on dose deposited by longitudinal and transverse structured beams}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- literature research on which effect affect dosimetry of ultra short, high intensity dose rate beams}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- ?develop model based on measurements in publication and extend to higher dose rates/shorter pulses?}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
Simulations:}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- evaluate the different operation modes of FLUTE (varying pulse length and charge) with respect towards dose rate of final electron beam, with e.g. FLUKA/EGSnrc}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- simulate the 6D particle distribution expected at the exit of the linear}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
accelerator, employing e.g. ASTRA (gun to start compressor with Space charge) and OCELOT (through compressor with CSR)}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\tab -simulate different possibilities to achieve structure beam at exit:}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\tab - spatial light modulator also used for longitudinal modulation via spectral modulation?}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\tab - energy modulation turned spatial with spectrometer magnet at exit}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\tab - ?}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- followed by simulation of the beam dynamics for this particle distribution on its trajectory}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
to the target, based on existing simulation tools and models, e.g. transport/covariance matrices combined with average scattering angles based on existing beam-matter interaction descriptions}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- study deformation of the temporal and spatial distribution on the way through the accelerator and outside on the way to the target under the influence of collective effects, e.g. space charge and the influence of impedances}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\tab - sometimes simulation of particles with matter interaction only (e.g. only linear boltzman \tab equation in kit-rt?), not with each other. Here add collective effects based on knowledge \tab from accelerator, eg. space charge...(what else is there without magnets/bends?)}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- Investigate link between starting distribution and output beam structure exists, by starting with custom, artificial test structures and simulate resulting structure at output, can the transformation be calculated without using particle tracking. (input of knowledge of accelerator optics/model is okay)}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- develop calculation to define starting distributions in order to achieve specific output distributions (which could be based on requested beam structures defined by the results in RT developments)}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
-}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- simulate the differences in deposited dose (2D) depending on initial distribution accelerator as well as in dependence on inclusion of the collective effects during beam transport.}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- create combined simulation which includes all three parts the beam dynamic in the accelerator and the propagation through matter to the target and finally the deposited dose.}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
Experimental:}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- survey of required vs available diagnostics to measure/determine 6D particle distribution at different positions in the linac, e.g. virtual diagnostic available}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- measurements of 6D particle distribution at accelerator exit and investigate dependence on accelerator parameters, e.g. pulse length, charge, starting distribution}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\tab test different possibilities to achieve structure beam at exit:}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\tab - masks?}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\tab - spatial light modulator also used for longitudinal modulation via spectral modulation?}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\tab - energy modulation turned spatial with spectrometer magnet at exit}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\tab - zwei quads to blow up and then collimate beam with the bigger size}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\tab - use SLM to change spot on cathode shot by shot, and therefore, change (e.g.) scan e \tab beam. is this simpler, than scanning with a magnet?}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- set up necessary diagnostic/detectors/targets for dose rate measurement in air and in a water target (including market survey and acquisition)}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- investigate dependence of measured dose on accelerator parameters such as pulse length, charge, longitudinal/transverse structure? ENERGY! ...}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- expand setup to allow for detection of spatial distribution, (could be film Kodak XV-2 silver halide radiographic film and thermoluminescent dosimeter TLD-100 as in (}{{\field{\*\fldinst HYPERLINK "https://doi.org/10.1016/S0958-3947(02)00086-9" }{\fldrslt {\hich\af6\loch\cf2\fs24\ul\ulc0\b0\f6\dbch\af13\langfe1033\loch
https://doi.org/10.1016/S0958-3947(02)00086-9}{}}}\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
)) or what about a detector like (27x27cm? Oder doch 4x4cm?? https://www.ptwdosimetry.com/en/products/octavius-detector-1500}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- experimental studies of the propagation of 6D particle distribution through air and/or}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
water, structuring done by mask at accelerator exit as well as structured by gun or dynamic in linac}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- extend studies to X-ray(/THz?) at synchrotron light source (KARA)????????}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
for micro beams, normally used mask, probably no way to get electrons per-structured???}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
for FLASH, problem high reprate? }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- and/or electrons from Lpaccelerator\u8230\'85}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- hit tests mit protonen? (was testen)}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
Periodical cross-checks between experimental results and simulations to iteratively improve both}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
TODO: }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- use detector that allows for 2d transverse distribution measurement\u8230\'85.or can 2d dose be calculated from 2d distribution measurement with e.g. screen?? how does longitudinal distribution affect this????}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- MASTER STUDENTS? Chance for postdoc to collect experience in supervising students\u8230\'85}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
folgende punkte offen wo master student passt und bekomme weil vorlesung halten.../praktikum...(vlt auch versuch erneuern...)}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
--------------}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
starting point: }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
me (year 1): review of existing simulation tools and methods on accelerator side as well as on beam matter interaction side\u8230\'85.starting point electron beam from FLUTE }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
phd1 (year 1&2&3): experimental setup and diagnostic for structured electron beam at/after flute, extend beyond accelerator and into phantom/target/ \u8230\'85.charge distribution outside vaccum/after matter interaction & dosimetry, ...dependence on structured beam...see in plan}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0
\u8594\'3f }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
provide input for simulations and later cross-checks with simulation based on measurement results}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
me (year1) find postdoc }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
postdoc(year 2&3): extend and combine simulations and new implement new methods to propagate structured beams through matter interaction, based on the existing simulations like MC but also transport matrix stuff, include not only single electron matter effects but also consider collective effects during transport through matter for electrons}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
?think about x-rays from KARA?}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
me(year 2&3)???think about x-rays from KARA? }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
(Somewhere I could do something with systematic simulation (computational experiments) using high performance computing???)}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
((ALTERNATIVE: I do postdoc as described above, and postdoc does improvements on (time-resolved?) dosimetry\u8230\'85for ultra short pulses, would need to be detector engineer \u8230\'85.))}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
Phd2 (year4&5&6): }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
based on previous results work on algorithm/method to adjust starting distribution in such a way that the a certain \u8220\'93requested\u8221\'94 distribution on target is achieved by pre-compensating(??) the expected effects of transport through accelerator and matter\u8230\'85.}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
me(year 4&5&6) ???}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
((ALTERNATIVE year 4-6: using Cstart for \u8220\'93energy scanning\u8221\'94 and \u8220\'93pulse length\u8221\'94 scanning measurement, to test effects on beam matter interaction during transport of structured beams and dosimetry...For this out-coupling of electrons necessary at cstart))}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
interface zwischen simulation und messung, }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
multi-facceded simulation, mutli-stage}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
state of the art, vs was ich nach mir, was m\u246\'f6chte ich addressieren, was m\u246\'f6chte l\u246\'f6sen}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
allein stellungsmerkmal herausarbeiten}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
ganz konkret was sind die probleme die zu adressieren sind, was sind die wow effekte}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
space charge, micro-bunching, \u252\'fcbergangsstrahlung (bei material wechsel) }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
viele kleine punkte (vergleich pepperpot emittance messen, andree diss)}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
raumladung bei detektion}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
statistische l\u246\'f6sung, strahl als ensemble, beam als ensemble, streueigenschaften, reihe streuung, matirxmultiplikationen. Covariance matrix ansatz (statistische matrizen)\u8230\'85}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
diagnostic problem, durch kurz strahl pulse}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s2\rtlch\af16\afs20\alang1025\ai\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx576\hyphpar0\faauto\li576\ri0\lin576\rin0\fi-576\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 2.4\tab}\ilvl1\ls1 \li1152\ri0\lin1152\rin0\fi-576\sl288\slmult1\tx576{\loch
Handling of research data}{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate 1203835956}\loch\sl240\slmult1\loch{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
. We will follow Open Science principles, generate}\par\loch\sl240\slmult1{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
FAIR (Findable, Accessible, Interoperable, Reusable) data,}}}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0{\loch\lang1033\b0\loch
The research data produced in this project will cover a wide variety of data types, sizes and formats. Measurement data will originate from the multitude of accelerator beam diagnostic system such as charge measurement, beam position information, transversal bunch profiles monitors or gun laser parameter}{\rtlch\ab0 \ltrch\lang1033\loch\lang1033\b0\loch
s, as well as from dose measurements in the water phantom.}{\loch\cf20\lang1033\b0\loch
}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
Estimating the total amount of measurement data to be generated over the course of the 6 year project duration results in several TBytes due to the multitude of diagnostics continuously running during the accelerator experiments combined with systematic parameter scans including imaging data from 2D profile measurements. }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
Simulation will be conducted with multiple existing simulation tools like EGSnrc, FLUKA, ASTRA or Ocelott (add citation!). Furthermore, results from theoretical calculations such as self implemented simulation tools are expected and will contribute to the resulting research data as well as the developed software tools themselves. Due to the use of particle tracking simulation tools and the possibility to run}{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate 1740708789}\loch\sl240\slmult1\loch{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
Have experience with HPC for running simulations}}}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
simulations on a HPC cluster}{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate 1740708788}\loch\sl240\slmult1\loch{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
HoreKa, mention here?}}}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
, the estimated amount of simulation data is also in the range of several TBytes. }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate 1740708790}\loch\sl240\slmult1{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
Not mentioned until now: post processing&analyzing (extract specific parameters, like a value for bunch size from screen recording, FFT,... plotting...)? Systematic comparison for parameter scan and with simulated values? - most will be done in python (much experience), matlab and what ever the used simulation tools are programmed in}\par\loch\sl240\slmult1{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
programming languages including python, matlab, \uc3 \u8230\'e2\'80\'a6.\uc1 }\par\loch\sl240\slmult1{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
size/data volume?? approx 10 TByte in sum?}}}{\loch\lang1033\b0\loch
The file formats will depend on the diagnostic systems or simulation tools and can range from for example TXT, PNG, JSON or CSV to proprietary file formats such as MAT (Matlab) or custom binary file-formats. If the original format is not easily accessible and/or additional metadata should be saved with the original data, the data will be transferred into files of the hdf5 file-format (Hierarchical Data Format version 5).}{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate 1740708586}\loch\sl240\slmult1\loch{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
@online\{hdf5,}\par\loch\sl240\slmult1{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
author = \{\{The HDF Group\}\},}\par\loch\sl240\slmult1{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
date-added = \{2019-10-29 20:36:49 +0100\},}\par\loch\sl240\slmult1{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
date-modified = \{2019-10-29 21:07:12 +0100\},}\par\loch\sl240\slmult1{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
title = \{\{Hierarchical Data Format, version 5\}\},}\par\loch\sl240\slmult1{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
url = \{https://www.hdfgroup.org/HDF5/\},}\par\loch\sl240\slmult1{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
year = \{1997-2019\},}\par\loch\sl240\slmult1{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
bdsk-url-1 = \{https://www.hdfgroup.org/HDF5/\}\}}}}{\loch\lang1033\b0\loch
In}{\rtlch\ab0 \ltrch\lang1033\loch\lang1033\b0\loch
the past, I have used }{\loch\lang1033\b0\loch
the hdf5 file-format extensively and it has proven to be very useful to store complex data, as it is accessible with a wide variety of programming languages (e.g. Python, Matlab, C++) and provides the possibility for internal structuring the stored data in groups, multi-dimensional datasets and amend each substructure with attributes. This allows the collection of connected data, such as the output of different diagnostic tools during one experiment, as well as the addition of metadata. In this way all the information from different sources needed to evaluate measurement results including information about the used instrument types, configuration and settings and furthermore operational parameters of the accelerator. The same principle can be applied to data resulting from calculations and simulations. In this case, it is possible to for example save different derived properties of the simulation output additionally to the simulation results or combine output given in multiple files into one. And furthermore, to keep the context of the simulation and improve the re-usability, all the simulation input parameters and settings can be stored as metadata in the attributes of the hdf5-files. }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
Also in cases, where the stored data is not in SI units conversion factors can be included in the metadata}{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate 1740708681}\loch\sl240\slmult1\loch{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
Reference to Inovesa??}}}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
. }{\loch\lang1033\b0\loch
In cases where the read-out software or the simulation tool will be programmed from scratch, the hdf5 file-format will be used directly. }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
A consistent filename convention will be implemented including the date (in the human readable date format ISO8601), a short name for the detector respective the simulation tool, and further information. Additional information relevant for later analysis or re-use of the data will be, as mentioned earlier, saved as metadata, either live during the measurement, for example, by reading accelerator parameters provided online from the accelerator control-system (EPICS) (always including Unix timestamps for each added parameter) or, alternatively, added later on in post-processing. All relevant accelerator settings, parameters or properties are by design saved continuously in a Casandra database. A corresponding post-processing workflow can be based on an existing Python framework}{\rtlch\afs28 \ltrch\lang1033\loch\cf20\lang1033\b0\loch
}{\rtlch\ab0 \ltrch\lang1033\loch\lang1033\b0\loch
developed by me which was successfully used to process more than 50 TByte of measurement data during my PhD studies. }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
To document the conducted experiments, the digital logbook ELOG }{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate 1740708911}\loch\sl240\slmult1\loch{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
https://elog.psi.ch/elog/}}}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
will be used. Originally developed at the Paul Scherrer Institut (Switzerland) under the GNU Public License, it is used in multiple accelerator facilities as a documentation standard. Small data files can be directly linked to the corresponding entries. Larger files will be stored in structured directories on a file server of the institute and a link to the storage location will be added to the ELOG entry. For documentations exceeding the logging during individual measurements, an instance of a wiki is available at the institute. Sub-spaces for individual teams can be created with corresponding access rights. There, information or discussions regarding multiple measurements or simulations can be stored. Within the framework of scientific research, regular comparisons between simulated and measured data will be performed to ensure consistency and increase data quality. Furthermore regular reference measurements at well known conditions are performed to characterize the detection chains. Regular meetings and discussions on the acquired data will be held to minimize human bias (four eyes principle). For the development of software a GitLab}{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate 1740708944}\loch\sl240\slmult1\loch{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
https://about.gitlab.com/}}}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
instance will be used. This provides a version controlled and simple possibility to save, transfer and jointly work on source codes. With the usage of GIT}{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate 1740708942}\loch\sl240\slmult1\loch{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
https://git-scm.com/}}}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
(distributed version control system), there is also the possibility to implement basic quality control mechanisms, e.g. git hook frameworks like pre-commit}{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate 1740708941}\loch\sl240\slmult1\loch{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
https://pre-commit.com/}}}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
, which check the integrity of the source code before committing. For all python scripts the PEP8 coding-style convention will be respected. }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
For immediate storage during the runtime of the project, the data will be saved on the institute\u8217\'92s own servers which are equipped with backups and allow to manage the access rights via user-groups. A specific group directory would be created with a systematic folder structure to allow the storage of the generated measurement and simulation data sorted by type and date. In addition to ensure minimal data loss every personal pc of group members will be equipped with an external backup hard drive and each member will be instructed to perform regular backups.}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
For long-term storage and archival of data the multi-petabyte storage systems of the host institution (e.g. LSDF) including the archival on tape storage will be used. A minimum storage period of 10 years is default for these services. Those are provided by the host institution at no cost. In addition, RADAR4KIT, a research data repository, can be used to, to bundle data and metadata, store and archive this data with the possibility to provide public access later on. For publications, high-level derivative data can be added as supplementary material on the journal web-page. For simulation data, produced with publicly available simulation code, the minimal set of parameters to recreate the simulations will be added. The corresponding full data sets can be published in KITopen via RADAR4KIT, receive a DOI and is open access. Software developed in the framework of this project is planned to be open-source and published on services such as GitHub.}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
Members of the project group will be provided with the possibility to learn the usage of technologies regarding data management used for the project. Due to the continuous availability throughout the project and previous experiences with large data and software management, the applicant will take on the task of coordinating the handling of research data for the project supported by the IT team of the host institute. Since the usage of established storage solutions is foreseen, the long-term storage and archival responsibility after the project ends lies with KIT.}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
Research data management within the project as well as the used services will conform to the guidelines published by KIT (\u8220\'93Guidelines for Responsible and Sustainable Research Data Management at KIT (RDM Policy)\u8221\'94) as well as the DFG code of conduct, and the EU open science policy.}{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate 1203835785}\loch\sl240\slmult1\loch{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
https://www.rdm.kit.edu/english/researchdata_policies_kit.php}}}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s2\rtlch\af16\afs20\alang1025\ai\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx576\hyphpar0\faauto\li576\ri0\lin576\rin0\fi-576\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 2.5\tab}\ilvl1\ls1 \li1152\ri0\lin1152\rin0\fi-576\sl288\slmult1\tx576{\loch
Relevance of sex, gender and/or diversity}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang2057\loch\lang2057\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs22 \ltrch\loch\b0\loch
[Text] not relevant for proposed project content, but want to contribute to \u8230\'85.diversity in gender, background, nationality, \u8230\'85.by\u8230\'85}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs22 \ltrch\loch\b0\loch
welcoming and inclusive work environement for international researchers (international office KIT?) (as I have experienced it during my time abroad) for example by establishing the group internal comunication in German and English, and ...}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs22 \ltrch\loch\b0\loch
want to be an excample and role model for young female researchers/young women in science(?) and inform and enable possible female students/group members to join workshops/conferences towards female researchers \u8230\'85EXAMPLE (something that does not cost and does not take away from the male students)}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs22 \ltrch\loch\b0\loch
\par \pard\plain \s2\rtlch\af16\afs20\alang1025\ai\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx576\hyphpar0\faauto\li576\ri0\lin576\rin0\fi-576\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 2.6\tab}\ilvl1\ls1 \li1152\ri0\lin1152\rin0\fi-576\sl288\slmult1\tx576{\loch
Justification for the choice of host institution(s)}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\fs18\lang2057\i\b0\loch
Please justify the choice of each proposed host institution.}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
The Karlsruhe Institute of Technology (KIT) would provide an exceptionally well-suited research environment with an unique combination of multidisciplinary research infrastructure and strategic collaborations within the multitude of institutes in complementary research fields as well as with external institutions. }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
The KIT is one of the eleven \u8220\'93Universities of Excellence\u8221\'94 in Germany. It is unique in that it combines a university and a national research laboratory (in the Helmholtz Association) within one entity resulting in one of the biggest science institutions in Europe. These conditions provide the opportunity to combine academic and fundamental research with application-based and goal-oriented research. KIT offers the possibility to profit from the motivation and ingenuity of students and early-carrier researchers and at the same time gives access to large-scale research facilities. }{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate 666963186}\loch\sl240\slmult1\loch{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
AUCH M\uc2 \u214\'c3\'96GLICHKEIT ZU LEHRE- also 100 new professorships going to be established\uc3 \u8230\'e2\'80\'a6.?\uc1 }}}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
The excellent research at KIT covers among others the disciplines of natural and engineering sciences. Interdisciplinary KIT Centers bring together scientists from different institutes to cross-divisionally tackle challenges and research actives connected to the further development and technological improvement of society. This quest naturally leaves KIT striving to push also the advancement of medical technologies. As newest of the nine KIT Centers, the Center \u8220\'93Health Technologies\u8221\'94}{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate 666963214}\loch\sl240\slmult1\loch{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
\uc3 \u8220\'e2\'80\'9cThe KIT Center \u8222\'e2\'80\'9eHealth Technologies\u8220\'e2\'80\'9c promotes the digital transformation of medical technologies, humanoid robotics, personalized medicine and health care to provide next generation innovation for the global health challenges of today and tomorrow.\u8221\'e2\'80\'9d\uc1 }}}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
has recently been established in March 2023 aiming to \u8220\'93provide next generation innovation for the global health challenges of today and tomorrow\u8221\'94}{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate 666963220}\loch\sl240\slmult1\loch{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
https://www.healthtech.kit.edu/index.php}}}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
.}{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate 666963186}\loch\sl240\slmult1\loch{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
...WAS hilft das? Health related research environment..}}}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
Another piece of the puzzle is the research bridge \u8220\'93Medical Technology for Health (MTH)\u8221\'94 with the aim to combine knowledge from engineering sciences, molecular basic research and bio-informatics with medical expertise to develop better diagnostics and therapy. The bridge is part of the longstanding strategic partnership with the Heidelberg University HEIKA (Heidelberg Karlsruhe Strategic Partnership)}{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate 666963231}\loch\sl240\slmult1\loch{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
(close connection provides access to Heidelberg research?? also HIT???)}}}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
which was initiated in order to combine the complementary competencies of the two Universities. Furthermore, a joint master program in medical engineering in cooperation with the University Heidelberg is planned to start in the winter semester 24/25}{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate 666963266}\loch\sl240\slmult1\loch{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
https://www.kit.edu/kit/english/pi_2022_051_new-medical-engineering-study-program-to-bridge-gap-between-people-and-technology.php}}}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
. }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- Hilft weil bringt die medicine componente mit rein...}{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate 666963242}\loch\sl240\slmult1\loch{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
-(CHECK OUT: Prof. Dr. Dr. J\uc2 \u252\'c3\'bcrgen Debus / Prof. Dr. Ivan Peri\uc1 }{\rtlch\alang1081\ai0\ab0\af21\afs28 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
\uc2 \u263\'c4\'87\uc1 }{\rtlch\alang1081\ai0\ab0\af18\afs24 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
Particle therapy beam monitoring with HV-CMOS sensors)}}}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- aufbruchstimmung gut um eine gruppe and der schnittstelle zwischen beschleuiniger und eben medizinischer technology zu etablieren und bietet viele wachstums m\u246\'f6glichkeiten im sinne von Kollaborationen mit instituten und experten au\u223\'dferhalb des eigenen forschungsfeldet \u8230\'85.}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- potential to contribute to this new focus point \u8230\'85..}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- auch lehre super da diese themen auch attractive f\u252\'fcr viele neue studenten sein wird...}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\cf20\lang1033\b0\loch
- collaboration with uniklinikum Heidelberg???}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
The Accelerator Technology Platform (ATP) at KIT combines KIT internal expertise and infrastructures relevant for accelerator research, development and application. This not only includes the KIT based accelerators FLUTE and KARA (see below), experts in accelerator physics (IBPT) and accelerator relevant technologies like the Magnet Characterization Facilities (MCF) and cryogenic research laboratories, but furthermore it also includes experts and infrastructure on advanced detector technologies studying for example ultra-fast and radiation hard detection systems.}{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate 666963236}\loch\sl240\slmult1\loch{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
\uc3 \u8230\'e2\'80\'a6..WAS bringt es mir\uc1 }\par\loch\sl240\slmult1{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
(check on: dosimetry, neutron detection}\par\loch\sl240\slmult1{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
and simulation of particle transport (R. Stieglitz, R. Engel, A. Ferrari), und auch mathematical models for dose calculations and RT treatment planning and simulation of}\par\loch\sl240\slmult1{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
oxygenation in tumor tissue (M. Frank))}}}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
}{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate 666962739}\loch\sl240\slmult1\loch{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
Kann das drin sein? Nein!}\par\loch\sl240\slmult1{\rtlch\ab0\ai0\alang1081\afs24\af18 \ltrch\lang1033\langfe2052\hich\af3\loch\lang1033\b0\ulnone\ulc0\strike0\shad0\charscalex100\i0\kerning0\fs20\f3\accnone\outl0\cf1\expnd0\expndtw0\scaps0\caps0\dbch\langfe2052\af21\loch
All the above is planned to serve as a foundation for a new Cluster of Excellence called AccelerateRT, aiming for basic research towards a more effective, efficient and widely available radiotherapy by focusing on tailored compact accelerators, corresponding beam control, dosimetry and visualization and the resulting bio-medical effects of novel radiotherapy qualities. }\par\loch\sl240\slmult1{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\langfe2052\lang1033\hich\af3\loch\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\kerning0\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\langfe2052\af21\loch
(We plan to build the scientific foundations of a new generation of}\par\loch\sl240\slmult1{\rtlch\ab0\af18\afs24\ai0\alang1081 \ltrch\lang1033\langfe2052\hich\af3\loch\cf1\f3\outl0\kerning0\expnd0\expndtw0\lang1033\ulnone\ulc0\accnone\fs20\strike0\scaps0\caps0\charscalex100\b0\i0\shad0\dbch\langfe2052\af21\loch
radiotherapy with the goal to substantially improve cancer cure rates. Our long-term vision is}\par\loch\sl240\slmult1{\rtlch\ab0\af18\afs24\ai0\alang1081 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\outl0\cf1\shad0\lang1033\charscalex100\accnone\b0\scaps0\caps0\f3\fs20\ulnone\ulc0\strike0\i0\expnd0\expndtw0\dbch\langfe2052\af21\loch
to translate this basic research into more effective, efficient and widely available radiotherapy.}\par\loch\sl240\slmult1{\rtlch\ab0\af18\afs24\ai0\alang1081 \ltrch\lang1033\langfe2052\hich\af3\loch\cf1\f3\outl0\kerning0\expnd0\expndtw0\lang1033\ulnone\ulc0\accnone\fs20\strike0\scaps0\caps0\charscalex100\b0\i0\shad0\dbch\langfe2052\af21\loch
The basic research in AccelerateRT will focus on three major areas: (A) tailored compact}\par\loch\sl240\slmult1{\rtlch\ab0\af18\afs24\ai0\alang1081 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\outl0\cf1\shad0\lang1033\charscalex100\accnone\b0\scaps0\caps0\f3\fs20\ulnone\ulc0\strike0\i0\expnd0\expndtw0\dbch\langfe2052\af21\loch
accelerators, (B) beam control, dosimetry and visualization of irradiation efficacy, and}\par\loch\sl240\slmult1{\rtlch\ab0\af18\afs24\ai0\alang1081 \ltrch\lang1033\langfe2052\hich\af3\loch\cf1\f3\outl0\kerning0\expnd0\expndtw0\lang1033\ulnone\ulc0\accnone\fs20\strike0\scaps0\caps0\charscalex100\b0\i0\shad0\dbch\langfe2052\af21\loch
(C) exploration of bio-medical effects and optimization of novel radiotherapy qualities. )}\par\loch\sl240\slmult1{\rtlch\alang1023\af23 \ltrch\lang1023\langfe1023\hich\af3\loch\f3\fs24\b0\kerning0\lang1023\dbch\langfe1023\af22\loch
}}}{\loch
}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
With the experimental part of the proposed project relying on the possibility to conduct systematic measurement on accelerators and beams, KIT with the Institute for Beam Physics and Technology (IBPT) is an ideal environment in that it provides easy and extended access for in-house researchers to its electron accelerators. Both accelerators serve as accelerator test facilities for a variety of accelerator physics studies, leading to a high flexibility in available operation modes and beam conditions and the possibility to tailor operation modes to experimental requirements. To this end the accelerators are equipped with extensive, state of the art diagnostics and continuously serve as a test-bed for research towards novel and improved diagnostic methods. }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
The 2.5 GeV storage ring and synchrotron light source KARA}{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate 666963016}\loch\sl240\slmult1\loch{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
The research infrastructure (RI) Karlsruhe Research Accelerator (KARA) provides a 2.5-GeV storage ring and light source for experiments with electron beams and intense electromagnetic, synchrotron radiation for deep insights into matter, in biological structures and materials. KARA as a test facility, together with other RIs within the Accelerator Technology Platform (ATP) at KIT support R&D of technologies for tomorrow's accelerators and detectors. This covers a broad method spectrum from superconducting magnet technology, simulation and modelling, novel diagnostics, via ultra-fast detectors and readout electronics, digitization, AI incl. machine learning, robotics, to laser-based accelerators. Jointly, scientists from KARA and Energy Lab 2.0 address global challenges in the area of energy, fostering novel concepts for current and future RIs focusing on sustainable energy solutions from components to systems. KARA is operated and developed by IBPT and also in use in research-oriented teaching and for innovation.}}}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
(Karlsruhe Research Accelerator) is based on the ANKA (Angstr\u246\'f6mquelle Karlsruhe) which started operation in 2003 and which has been improved continuously since then. KARA provides short-pulsed x-ray modalities at multiple beam lines. Further more, }{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate 666963008}\loch\sl240\slmult1\loch{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
Neue powersupplies daher bessere stabilit\uc2 \u228\'c3\'a4t im kurz pulse betrieb, aber paper noch nicht published, erst bei IPAC.\uc1 }}}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
additional operation modes have been implemented at different electron energies such as for example a short-pulse operation allowing the investigation of the dynamics in short electron bunches [Quelle mit mir?] as well as the development and tests of novel, fast diagnostic methods [auch Quelle mit mir?]. }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
The second accelerator at KIT-IBPT is the linear electron accelerator FLUTE (Ferninfrarot Linac- und Test-Experiment)}{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate 666962741}\loch\sl240\slmult1\loch{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
The new FLUTE facilitiy (name abbreviation derived from its German name: Ferninfrarot Linac- und Test-Experiment) at the Karlsruhe Institute of Technology (KIT), developed and operated by IBPT, serves as an accelerator test facility for a variety of accelerator physics studies.}\par\loch\sl240\slmult1{\rtlch\alang1023\af23 \ltrch\lang1023\langfe1023\hich\af3\loch\f3\fs24\b0\kerning0\lang1023\dbch\langfe1023\af22\loch
}\par\loch\sl240\slmult1{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
The core accelerator consists of a femtosecond chirped laser-driven photo-injector, a linear accelerator (linac) and an electron bunch compressor to provide ultra-short electron bunches. This compact versatile linear accelerator will also provide coherent radiation in ultra-short, very intense, light pulses spanning the terahertz and far-infrared spectral range and beyond. FLUTE also provides an infrastruture for picosecond and femtosecond electron and photon beam studies to enable future application-oriented research from materials to life sciences and innovative technology solutions such as advanced electron and photon beam diagnostics.}}}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
. It is designed to provide ultra-short electron pulses with an energy of around 6 MeV after the low-energy section and with energies of up to 50 MeV and bunch lengths down to femtoseconds after the full accelerator. Furthermore, FLUTE provides coherent radiation in ultra-short, very intense light pulses from terahertz to far-infrared and beyond. The electrons pulses in FLUTE are generated with a femtosecond chirped laser-driven photo-injector. Recent studies include the application of machine learning for accelerator tuning tasks based on reinforcement learning as well as extend the existing diagnostics with virtual diagnostics achieved by surrogate modeling of the electron beam dynamics. Also of great importance is the recent implementation of a spatial light-modulator which allows spatial and temporal shaping of the laser pulse on the photo-cathode and therefore control of the initial electron distribution in the accelerator. }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
ADD SPLIT RING RESONATOR FOR BUNCH LENGTH MEASUREMENT?}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
CRUCIAL FOR PROJECT\u8230\'85. }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
PERFECT FOR INVESTIGATIONS OF FLASH LIKE RT BEAM MODALITIES...}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\qj\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
Besides the two existing accelerators, two more are planned to be build within the near future. A 50 MeV laser-plasma accelerator is being build as part of the ATHENA project}{
{\*\atnid }{\*\atnauthor Unknown Author}\chatn{\*\annotation{\*\atndate 666963153}\loch\sl240\slmult1\loch{\rtlch\af18\afs24\alang1081\ai0\ab0 \ltrch\lang1033\langfe2052\hich\af3\loch\kerning0\scaps0\caps0\expnd0\expndtw0\cf1\outl0\accnone\f3\fs20\lang1033\i0\charscalex100\shad0\strike0\ulnone\ulc0\b0\dbch\af21\langfe2052\loch
ATHENA, https://www.athena-helmholtz.de/home/index_eng.html, May 2022.}}}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
in collaboration with DESY and the Helmholtz Institute Jena (HIJ). This will open the opportunity to test the developed simulation and diagnostic methods to a different type of accelerator and investigate the possibilities and limitations of LPA beams for radiotherapy. Last but not least, an innovative non-equilibrium storage ring with a wide energy acceptance will be build and will be able to accept both, the LPA as well as FLUTE, as injector. Storing the sub-picosecond to femtosecond short beams will lead to continuous electron bunch lengthening over the revolutions and will provide the possibility to study the effects of different pulse lengths on the detected dosage. }
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\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
IBPT -AI? Help with computations and modeling?}
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Even tough alma mater \u8211\'96 unparalleled opportunities, due to unique environment at KIT\u8230\'85.}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
Strong advantage as provides accelerator based high-intensity x-ray beams as well as ultra-short pulse electron beams at the same institution\u8230\'85..}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
perfect fit for experimental part, and due to many existing centers, clusters, and collaborations great, nurturing environment also for multi-disciplinary input and solutions.}
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\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
Embedded in one of Germany\u8217\'92s leading healthcare and technology regions, }{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
(}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
AccelerateRT}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
)}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
is}
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especially well positioned to\u8230\'85...}
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\par \pard\plain \s1\rtlch\af13\afs24\alang1025\ab \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx432\hyphpar0\faauto\li432\ri0\lin432\rin0\fi-432\keepn\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\loch\fs22\i0\b 3\tab}\ilvl0\ls1 \li864\ri0\lin864\rin0\fi-432\sl288\slmult1\tx432{\loch\lang1033\loch
Project- and subject-related list of publications}
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Works cited from sections 1 and 2, both by the applicant and by third parties. Please include DOI/URL if available. }{\loch\fs18\lang2057\i\loch
A maximum of ten}{\loch\fs18\lang2057\i\b0\loch
of your own works cited may be }{\loch\fs18\lang2057\i\loch
highlighted}{\loch\fs18\lang2057\i\b0\loch
; font at least Arial 9 pt.}
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[Text]}
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Supplementary information on the research context}
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Section 4 et seq. must not exceed 8 pages.}
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Ethical and/or legal aspects of the project}
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General ethical aspects}
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[Text]}
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Descriptions of proposed investigations involving humans, human materials}{\rtlch\af13\ab0 \ltrch\lang2057\loch\lang2057\dbch\af13\loch
}{\loch\lang2057\loch
or identifiable data}
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[Text]}
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Descriptions of proposed investigations involving experiments on animals}
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[Text]}
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Descriptions of projects involving genetic resources (or associated traditional knowledge) from a foreign country}
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[Text]}
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Explanations regarding any possible safety-related aspects (\u8220\'93Dual Use Research of Concern; foreign trade law)}
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[Text]}
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\par \pard\plain \s2\rtlch\af16\afs20\alang1025\ai\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx576\hyphpar0\faauto\li576\ri0\lin576\rin0\fi-576\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 4.2\tab}\ilvl1\ls1 \li1152\ri0\lin1152\rin0\fi-576\sl288\slmult1\tx576{\loch
Employment status information}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\fs18\lang2057\i\b0\loch
Last name, first name, and employment status (including duration of contract and funding body, if on a fixed-term contract)}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs22 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs22 \ltrch\lang1033\loch\lang1033\b0\loch
[Text]}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs22 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s2\rtlch\af16\afs20\alang1025\ai\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx576\hyphpar0\faauto\li576\ri0\lin576\rin0\fi-576\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 4.3\tab}\ilvl1\ls1 \li1152\ri0\lin1152\rin0\fi-576\sl288\slmult1\tx576{\loch
Composition of the project group}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\fs18\lang2057\i\b0\loch
List only those individuals who will work on the project but will not be paid out of the project funds. State each person\u8217\'92s name, academic title, employment status, and type of funding.}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs22 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
[Text]}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\af16\afs28\ai\ab \ltrch\lang2057\loch\lang2057\b0\loch
\par \pard\plain \s2\rtlch\af16\afs20\alang1025\ai\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx576\hyphpar0\faauto\li576\ri0\lin576\rin0\fi-576\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 4.4\tab}\ilvl1\ls1 \li1152\ri0\lin1152\rin0\fi-576\sl288\slmult1\tx576{\loch
Researchers in Germany with whom you have agreed to cooperate on this project}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang2057\loch\lang2057\b0\highlight7\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang2057\loch\lang2057\b0\loch
[Text] Oliver J\u228\'e4kel }{\rtlch\afs28 \ltrch\lang2057\loch\lang2057\b0\loch
(}{\rtlch\afs28 \ltrch\lang2057\loch\lang2057\b0\loch
Heidelberg}{\rtlch\afs28 \ltrch\lang2057\loch\lang2057\b0\loch
)}{\rtlch\afs28 \ltrch\lang2057\loch\lang2057\b0\loch
, Anke, }{\rtlch\afs28 \ltrch\lang2057\loch\lang2057\b0\loch
Erik, }{\rtlch\afs28 \ltrch\lang2057\loch\lang2057\b0\loch
Lennart Volz?, }{\rtlch\afs28 \ltrch\lang2057\loch\lang2057\b0\loch
}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang2057\loch\lang2057\b0\highlight7\loch
\par \pard\plain \s2\rtlch\af16\afs20\alang1025\ai\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx576\hyphpar0\faauto\li576\ri0\lin576\rin0\fi-576\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 4.5\tab}\ilvl1\ls1 \li1152\ri0\lin1152\rin0\fi-576\sl288\slmult1\tx576{\loch
Researchers abroad with whom you have agreed to cooperate on this project}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang2057\loch\lang2057\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\loch\b0\loch
[Text]}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\loch\b0\loch
\par \pard\plain \s2\rtlch\af16\afs20\alang1025\ai\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx576\hyphpar0\faauto\li576\ri0\lin576\rin0\fi-576\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 4.6\tab}\ilvl1\ls1 \li1152\ri0\lin1152\rin0\fi-576\sl288\slmult1\tx576{\loch
Researchers with whom you have collaborated scientifically within the past three years}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\fs18\lang2057\i\b0\loch
This information will help avoid potential conflicts of interest.}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang2057\loch\lang2057\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
MAX IV, University Lund, Sweden: Dr. Pedro Fernandes Tavares, Dr. \u197\'c5ke Andersson}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
PhLAM, University Lille, France: Prof. Dr. Serge Bielawski, Dr. Christophe Szwaj}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
KIT, Germany: Prof. Dr. Anke-Susanne M\u252\'fcller, Dr. Erik Br\u252\'fcndermann}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s2\rtlch\af16\afs20\alang1025\ai\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx576\hyphpar0\faauto\li576\ri0\lin576\rin0\fi-576\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 4.7\tab}\ilvl1\ls1 \li1152\ri0\lin1152\rin0\fi-576\sl288\slmult1\tx576{\loch
Project-relevant cooperation with commercial enterprises}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\fs18\lang2057\i\b0\loch
If applicable, please note the EU guidelines on state aid or contact your research institution in this regard.}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch\fs18\lang2057\i\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
[Text]}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s2\rtlch\af16\afs20\alang1025\ai\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx576\hyphpar0\faauto\li576\ri0\lin576\rin0\fi-576\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 4.8\tab}\ilvl1\ls1 \li1152\ri0\lin1152\rin0\fi-576\sl288\slmult1\tx576{\loch\lang1036\loch
Project-relevant participation in commercial enterprises}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\fs18\lang2057\i\b0\loch
Information on connections between the project and the production branch of the enterprise}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs22 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs22 \ltrch\lang1033\loch\lang1033\b0\loch
[Text]}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs22 \ltrch\lang1033\loch\lang1033\i\b0\loch
\par \pard\plain \s2\rtlch\af16\afs20\alang1025\ai\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx576\hyphpar0\faauto\li576\ri0\lin576\rin0\fi-576\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 4.9\tab}\ilvl1\ls1 \li1152\ri0\lin1152\rin0\fi-576\sl288\slmult1\tx576{\loch
Scientific equipment}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\fs18\lang2057\i\b0\loch
List larger instruments that will be available to you for the project. These may include large computer facilities if computing capacity will be needed. }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
FLUTE }{\rtlch\afs28 \ltrch\lang1033\loch\cf20\lang1033\b0\loch
(is this first time mentioning FLUTE\u8230\'85?)}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
KARA,....}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
HPC (Rechenzentrum?) }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
"Use of HoreKa ("Hochleistungsrechner Karlsruhe") is free of charge, but the resource has to be acknowleged on all publications." (project proposal needs to be submitted)}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
bwUniCluster "All members of the shareholder universities can apply for an account. The use of the bwUniCluster is free of charge. "}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s2\rtlch\af16\afs20\alang1025\ai\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx576\hyphpar0\faauto\li576\ri0\lin576\rin0\fi-576\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 4.10\tab}\ilvl1\ls1 \li1152\ri0\lin1152\rin0\fi-576\sl288\slmult1\tx576{\loch
Other submissions}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\fs18\lang2057\i\b0\loch
List any funding proposals for this project and/or major instrumentation previously sub-mitted to a third party. }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
[Text]}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s2\rtlch\af16\afs20\alang1025\ai\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx576\hyphpar0\faauto\li576\ri0\lin576\rin0\fi-576\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 4.11\tab}\ilvl1\ls1 \li1152\ri0\lin1152\rin0\fi-576\sl288\slmult1\tx576{\loch
Other Information}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\fs18\lang2057\i\b0\loch
Please use this section for any additional information you feel is relevant which has not been provided elsewhere.}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang2057\loch\lang2057\b0\highlight16\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
[Text]}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch\lang1033\loch
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\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s1\rtlch\af13\afs24\alang1025\ab \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx432\hyphpar0\faauto\li432\ri0\lin432\rin0\fi-432\keepn\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\loch\fs22\i0\b 5\tab}\ilvl0\ls1 \li864\ri0\lin864\rin0\fi-432\sl288\slmult1\tx432{\loch\lang1033\loch
Requested modules/funds}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\fs18\lang2057\i\b0\loch
Explain each item (stating last name, first name)}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs22 \ltrch\lang1033\loch\lang1033\loch
\par \pard\plain \s2\rtlch\af16\afs20\alang1025\ai\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx576\hyphpar0\faauto\li576\ri0\lin576\rin0\fi-576\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 5.1\tab}\ilvl1\ls1 \li1152\ri0\lin1152\rin0\fi-576\sl288\slmult1\tx576{\loch
Module Junior Research Group Leader}
\par \pard\plain \s442\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs18\lang1031\i\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\loch
Use this module to request funding for your position as project leader under the Emmy Noether Programme.}
\par \pard\plain \s442\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs18\lang1031\i\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch\lang1033\loch
\par \pard\plain \s442\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs18\lang1031\i\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\lang1033\loch
Clinician scientists may apply for a temporary substitute position instead of a position as junior research group leader. The relevant module can be found on the list of modules.}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
[Text] Eigene Stelle}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch\lang1033\b0\loch
\par \pard\plain \s2\rtlch\af16\afs20\alang1025\ai\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx576\hyphpar0\faauto\li576\ri0\lin576\rin0\fi-576\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 5.2\tab}\ilvl1\ls1 \li1152\ri0\lin1152\rin0\fi-576\sl288\slmult1\tx576{\loch
{\*\bkmkstart _Toc283038963}{\*\bkmkstart _Toc283017380}{\*\bkmkstart _Toc283017188}{\*\bkmkend _Toc283038963}{\*\bkmkend _Toc283017380}{\*\bkmkend _Toc283017188}Basi}{\loch
{\*\bkmkstart _Toc2830171881}{\*\bkmkstart _Toc2830389631}{\*\bkmkstart _Toc2830173801}{\*\bkmkend _Toc2830171881}{\*\bkmkend _Toc2830389631}{\*\bkmkend _Toc2830173801}c Module}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\tx576\li576\ri0\lin576\rin0\fi0\loch
\par \pard\plain \s3\rtlch\af16\afs24\alang1025\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx720\hyphpar0\faauto\li720\ri0\lin720\rin0\fi-720\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\loch\fs20\i0\b 5.2.1\tab}\ilvl2\ls1 \li1440\ri0\lin1440\rin0\fi-720\sl288\slmult1\tx720{\loch
Funding for Staff}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
[Text]2 doctoral students (75%), (100% f\u252\'fcr ingenieur)}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
1 postdoc }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
hiwi? (538Euro job)}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
Aufgabe (mit verweis auf arbeitsprogram) und ab wann}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
????(die gew\u252\'fcnschte Dauer der Besch\u228\'e4ftigung im Vorhaben,}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0
}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- die Vertragslaufzeiten sollten in der Regel der Projektlaufzeit entsprechen,}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0
}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- bei der Festlegung der Vertragslaufzeiten f\u252\'fcr wissenschaftliches Personal in der}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
Qualifizierungsphase sollte das Qualifizierungsziel des Stelleninhabers bzw.}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
der Stelleninhaberin angemessen ber\u252\'fccksichtigt werden.)}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s3\rtlch\af16\afs24\alang1025\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx720\hyphpar0\faauto\li720\ri0\lin720\rin0\fi-720\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\loch\fs20\i0\b 5.2.2\tab}\ilvl2\ls1 \li1440\ri0\lin1440\rin0\fi-720\sl288\slmult1\tx720{\loch
Direct Project Costs}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
[Text]}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s4\rtlch\af13\afs28\alang1025\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx864\hyphpar0\faauto\li862\ri0\lin862\rin0\fi-862\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 5.2.2.1\tab}\ilvl3\ls1 \li1726\ri0\lin1726\rin0\fi-864\sl288\slmult1\tx864{\loch
Equipment up to \u8364\'80 10,000, Software and Consumables}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
[Text]}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
-Safety equipment, like small dosimeters to measure area free after irradiation?}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
5000?}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
-building material for eg. halter im water target ?? and similar }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
6000? \u8594\'3f 1000 pro jahr}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- cables, adapter, connectors for readout of detectors\u8230\'85}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
6000?}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- amplifiers, attenuators, for readout}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
6000?}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- humidity measure...}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- portable external drives for each group member for backup of the working pc 4x1TB SSD (4x100\u8364\'80=400\u8364\'80)}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- desktop PC for new diagnostics 3000\u8364\'80 including at least 4 TB of internal storage}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- (laptop kann nicht finanziert werden? Oder doch? 4X2000\u8364\'80=8000\u8364\'80)}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
- monitors...}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
=11400}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s4\rtlch\af13\afs28\alang1025\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx864\hyphpar0\faauto\li862\ri0\lin862\rin0\fi-862\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 5.2.2.2\tab}\ilvl3\ls1 \li1726\ri0\lin1726\rin0\fi-864\sl288\slmult1\tx864{\loch
Travel Expenses}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
[Text]Teilnahme Konferenzen (1x pro doctorant, 2x f\u252\'fcr postdoc, Xx f\u252\'fcr mich? }
\par \pard\plain \s430\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl-276\slmult0\ql\widctlpar\hyphpar0\faauto\sb0\sa140\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
HIDSS4Health. }{{\field{\*\fldinst HYPERLINK "https://www.hidss4health.de/" }{\fldrslt {\hich\af6\loch\cf2\fs24\lang1033\ul\ulc0\b0\f6\dbch\af13\langfe1033\loch
https://www.hidss4health.de}{}}}\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
summer school}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s4\rtlch\af13\afs28\alang1025\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx864\hyphpar0\faauto\li862\ri0\lin862\rin0\fi-862\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 5.2.2.3\tab}\ilvl3\ls1 \li1726\ri0\lin1726\rin0\fi-864\sl288\slmult1\tx864{\loch
Visiting Researchers }{\loch\b0\loch
(excluding Mercator Fellows)}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
[Text]}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s4\rtlch\af13\afs28\alang1025\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx864\hyphpar0\faauto\li862\ri0\lin862\rin0\fi-862\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 5.2.2.4\tab}\ilvl3\ls1 \li1726\ri0\lin1726\rin0\fi-864\sl288\slmult1\tx864{\loch
Expenses for Laboratory Animals}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
[Text]}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s4\rtlch\af13\afs28\alang1025\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx864\hyphpar0\faauto\li862\ri0\lin862\rin0\fi-862\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 5.2.2.5\tab}\ilvl3\ls1 \li1726\ri0\lin1726\rin0\fi-864\sl288\slmult1\tx864{\loch
Other Costs}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
[Text]}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s4\rtlch\af13\afs28\alang1025\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx864\hyphpar0\faauto\li862\ri0\lin862\rin0\fi-862\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 5.2.2.6\tab}\ilvl3\ls1 \li1726\ri0\lin1726\rin0\fi-864\sl288\slmult1\tx864{\loch
Project-related Publication Expenses }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
[Text] bis zu 750/Jahr f\u252\'fcr normale Publikationen (geht das z.b. druckkosten Dissertationen?), oder auch f\u252\'fcr nenn Buch kapitel oder so?}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
(PRL ist ehr 3000-3500USD) Nature zwischen 1500-9000 }
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s3\rtlch\af16\afs24\alang1025\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx720\hyphpar0\faauto\li720\ri0\lin720\rin0\fi-720\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\loch\fs20\i0\b 5.2.3\tab}\ilvl2\ls1 \li1440\ri0\lin1440\rin0\fi-720\sl288\slmult1\tx720{\loch
{\*\bkmkstart _Toc2921109861}{\*\bkmkstart _Toc292110986}I}{\loch
{\*\bkmkend _Toc292110986}nstrumentation{\*\bkmkend _Toc2921109861}}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s4\rtlch\af13\afs28\alang1025\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx864\hyphpar0\faauto\li862\ri0\lin862\rin0\fi-862\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 5.2.3.1\tab}\ilvl3\ls1 \li1726\ri0\lin1726\rin0\fi-864\sl288\slmult1\tx864{\loch
Equipment exceeding \u8364\'80 10,000}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
[Text] Dosimetry detectors (e.g. mircoDiamond from PTW) 9000-11000 netto}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
maybe gest several detectors and also something 2d resolved?}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
water phantom kleines horizontales 6750\u8364\'80 (gro\u223\'dfes motoriziertes WP \u8594\'3f 52000\u8364\'80)}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s4\rtlch\af13\afs28\alang1025\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx864\hyphpar0\faauto\li862\ri0\lin862\rin0\fi-862\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 5.2.3.2\tab}\ilvl3\ls1 \li1726\ri0\lin1726\rin0\fi-864\sl288\slmult1\tx864{\loch
Major Instrumentation exceeding \u8364\'80 50,000}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
[Text]}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s2\rtlch\af16\afs20\alang1025\ai\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx576\hyphpar0\faauto\li576\ri0\lin576\rin0\fi-576\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 5.3\tab}\ilvl1\ls1 \li1152\ri0\lin1152\rin0\fi-576\sl288\slmult1\tx576{\loch
Module Temporary Clinician Substitute}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\fs18\lang2057\i\b0\loch
Clinician scientists may apply for a temporary substitute position instead of a position as junior research group leader. In addition, this module may be used to finance substitute medical personnel who will assume the patient-care responsibilities of the clinicians participating in your project.}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\highlight16\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
[Text]}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s2\rtlch\af16\afs20\alang1025\ai\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx576\hyphpar0\faauto\li576\ri0\lin576\rin0\fi-576\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 5.4\tab}\ilvl1\ls1 \li1152\ri0\lin1152\rin0\fi-576\sl288\slmult1\tx576{\loch
Module Mercator Fellows}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
[Text]}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s2\rtlch\af16\afs20\alang1025\ai\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx576\hyphpar0\faauto\li576\ri0\lin576\rin0\fi-576\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 5.5\tab}\ilvl1\ls1 \li1152\ri0\lin1152\rin0\fi-576\sl288\slmult1\tx576{\loch
{\*\bkmkstart _Toc294158007}{\*\bkmkstart _Toc283017394}{\*\bkmkstart _Toc283017268}{\*\bkmkstart _Toc283039063}{\*\bkmkstart _Toc283038977}{\*\bkmkstart _Toc283017202}Module Workshop}{\loch
{\*\bkmkend _Toc294158007}{\*\bkmkend _Toc283017394}{\*\bkmkend _Toc283017268}{\*\bkmkend _Toc283039063}{\*\bkmkend _Toc283038977}{\*\bkmkend _Toc283017202} Funding}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
[Text]}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s2\rtlch\af16\afs20\alang1025\ai\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx576\hyphpar0\faauto\li576\ri0\lin576\rin0\fi-576\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 5.6\tab}\ilvl1\ls1 \li1152\ri0\lin1152\rin0\fi-576\sl288\slmult1\tx576{\loch
{\*\bkmkstart _Toc283017201}{\*\bkmkstart _Toc294158006}{\*\bkmkstart _Toc283039062}{\*\bkmkstart _Toc283038976}{\*\bkmkstart _Toc283017393}{\*\bkmkstart _Toc283017267}Modul}{\loch
{\*\bkmkend _Toc283017201}{\*\bkmkend _Toc294158006}{\*\bkmkend _Toc283039062}{\*\bkmkend _Toc283038976}{\*\bkmkend _Toc283017393}{\*\bkmkend _Toc283017267}e Public Relations Funding}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
[Text]}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s2\rtlch\af16\afs20\alang1025\ai\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx576\hyphpar0\faauto\li576\ri0\lin576\rin0\fi-576\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 5.7\tab}\ilvl1\ls1 \li1152\ri0\lin1152\rin0\fi-576\sl288\slmult1\tx576{\loch
Module Standard Allowance for Gender Equality Measures}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\loch\fs18\lang2057\i\b0\loch
Please detail what measures are planned to promote diversity and equal opportunities.}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0
}{\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
[Text]}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\lang1033\loch\lang1033\b0\loch
\par \pard\plain \s2\rtlch\af16\afs20\alang1025\ai\ab \ltrch\lang1033\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\tx576\hyphpar0\faauto\li576\ri0\lin576\rin0\fi-576\keepn\ltrpar\cf0\f5\fs22\lang1033\b\kerning1\dbch\af12\langfe1031{\listtext\pard\plain \rtlch\af13 \ltrch\hich\af5\loch\f5\fs20\i0\b 5.8\tab}\ilvl1\ls1 \li1152\ri0\lin1152\rin0\fi-576\sl288\slmult1\tx576{\loch
Module Family Allowance}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\rtlch\afs28 \ltrch\loch\b0\loch
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0{\rtlch\afs28 \ltrch\loch\b0\loch
[Text]}
\par \pard\plain \s0\rtlch\af13\afs24\alang1025 \ltrch\lang1031\langfe1031\hich\af5\loch\sl288\slmult1\ql\widctlpar\hyphpar0\faauto\ltrpar\cf0\f5\fs22\lang1031\b\kerning1\dbch\af12\langfe1031\sl288\slmult1\li0\ri0\lin0\rin0\fi0\loch
\par }